Evidence map›Paper›PMID 36768525›Full record

ArticleInternational journal of molecular sciences2023

Nanoparticle-Mediated Drug Delivery of Doxorubicin Induces a Differentiated Clonogenic Inactivation in 3D Tumor Spheroids In Vitro.

Roxana Cristina Popescu, Verena Kopatz, Ecaterina Andronescu, Diana Iulia Savu, Wolfgang Doerr

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Roxana Cristina PopescuDepartment of Life and Environmental Physics, National Institute for R&D in Physics and Nuclear Engineering "Horia Hulubei", Reactorului Street, 30, 077125 Magurele, Romania.
Verena KopatzDepartment of Radiation Oncology, Medical University of Vienna, Waehringer Guertel, 18-20, 1090 Vienna, Austria.ORCID 0000-0002-7512-1398
Ecaterina AndronescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Politehnica University of Bucharest, Gheorghe Polizu Street, 1-7, 011061 Bucharest, Romania.ORCID 0000-0002-2226-5849
Diana Iulia SavuDepartment of Life and Environmental Physics, National Institute for R&D in Physics and Nuclear Engineering "Horia Hulubei", Reactorului Street, 30, 077125 Magurele, Romania.ORCID 0000-0002-0145-5176
Wolfgang DoerrDepartment of Radiation Oncology, Medical University of Vienna, Waehringer Guertel, 18-20, 1090 Vienna, Austria.

Funding

Austrian Agency for International Cooperation in Education and Research ICM-2018-10056European Social Fund 13530/16.06.2022 - SMIS code: 153734Ministerul Cercetării și Inovării 543 PED/2020Ministerul Cercetării și Inovării PN 19060203/2019Norway-Romania Grants RO-NO-2019-0510, CTR 41/2020
6 · The paper itself

Abstract

Involvement of 3D tumor cell models in the in vitro biological testing of novel nanotechnology-based strategies for cancer management can provide in-depth information on the real behavior of tumor cells in complex biomimetic architectures. Here, we used polyethylene glycol-encapsulated iron oxide nanoparticles for the controlled delivery of a doxorubicin chemotherapeutic substance (IONP

Indexed as

AdenocarcinomaAntineoplastic AgentsNanoparticlesUterine Cervical NeoplasmsCell Line, TumorDoxorubicinFemaleHumansSpheroids, CellularAntineoplastic AgentsDoxorubicindoxorubicindrug deliveryin vitro 3D tumor spheroidsiron oxide nanoparticlesradiosensitization

Identifiers

PMID36768525
PMCPMC9916819

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.