Evidence map›Paper›PMID 36768576›Full record

SynthesisInternational journal of molecular sciences2023

An ELOVL2-Based Epigenetic Clock for Forensic Age Prediction: A Systematic Review.

Ersilia Paparazzo, Vincenzo Lagani, Silvana Geracitano, Luigi Citrigno, Mirella Aurora Aceto, Antonio Malvaso, Francesco Bruno, Giuseppe Passarino, Alberto Montesanto

Abstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Physical Activity and Epigenetic Aging in Breast Cancer Treatment.International journal of molecular sciences · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ersilia PaparazzoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Vincenzo LaganiBiological and Environmental Sciences and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal 23952, Saudi Arabia.ORCID 0000-0002-6552-6076
Silvana GeracitanoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Luigi CitrignoNational Research Council (CNR)-Institute for Biomedical Research and Innovation-(IRIB), 87050 Mangone, Italy.ORCID 0000-0001-7410-7781
Mirella Aurora AcetoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.
Antonio MalvasoDepartment of Brain and Behavioral Sciences, IRCCS "C. Mondino" Foundation, National Neurological Institute, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-9691-0890
Francesco BrunoRegional Neurogenetic Centre (CRN), Department of Primary Care, ASP Catanzaro, 88046 Lamezia Terme, Italy.ORCID 0000-0003-1377-4489
Giuseppe PassarinoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0003-4701-9748
Alberto MontesantoDepartment of Biology, Ecology and Earth Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0002-9563-2216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prediction of chronological age from methylation-based biomarkers represents one of the most promising applications in the field of forensic sciences. Age-prediction models developed so far are not easily applicable for forensic caseworkers. Among the several attempts to pursue this objective, the formulation of single-locus models might represent a good strategy. The present work aimed to develop an accurate single-locus model for age prediction exploiting

Indexed as

AgingForensic GeneticsChild, PreschoolCpG IslandsDNA MethylationEpigenesis, GeneticFatty Acid ElongasesHumansELOVL2 protein, humanFatty Acid Elongasesage predictionELOVL2epigenetic clockmethylationpyrosequencing

Identifiers

PMID36768576
PMCPMC9916975

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.