Evidence map›Paper›PMID 36768591›Full record

ArticleInternational journal of molecular sciences2023

Enzyme Inhibition-Based Assay to Estimate the Contribution of Formulants to the Effect of Commercial Pesticide Formulations.

Elena N Esimbekova, Valeriya P Kalyabina, Kseniya V Kopylova, Victoria I Lonshakova-Mukina, Anna A Antashkevich, Irina G Torgashina, Kirill A Lukyanenko, Elena V Nemtseva, Valentina A Kratasyuk

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elena N EsimbekovaInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.ORCID 0000-0002-2560-3575
Valeriya P KalyabinaInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.
Kseniya V KopylovaLaboratory of Cell Molecular Physiology and Pathology, Scientific Research Institute of Medical Problems of the North of the Siberian Branch of the Russian Academy of Sciences, 660022 Krasnoyarsk, Russia.ORCID 0000-0002-5006-0429
Victoria I Lonshakova-MukinaInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.
Anna A AntashkevichInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.
Irina G TorgashinaInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.
Kirill A LukyanenkoInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.ORCID 0000-0002-1115-6735
Elena V NemtsevaInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.ORCID 0000-0003-1725-8625
Valentina A KratasyukInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.

Funding

Ministry of Science and Higher Education of the Russian Federation 0287-2021-0020Siberian Federal University Strategic Project "Gastronomic RnD Park"
6 · The paper itself

Abstract

Pesticides can affect the health of individual organisms and the function of the entire ecosystem. Therefore, thorough assessment of the risks associated with the use of pesticides is a high-priority task. An enzyme inhibition-based assay is used in this study as a convenient and quick tool to study the effects of pesticides at the molecular level. The contribution of formulants to toxicological properties of the pesticide formulations has been studied by analyzing effects of 7 active ingredients of pesticides (AIas) and 10 commercial formulations based on them (AIfs) on the function of a wide range of enzyme assay systems differing in complexity (single-, coupled, and three-enzyme assay systems). Results have been compared with the effects of AIas and AIfs on bioluminescence of the luminous bacterium

Indexed as

PesticidesBiological AssayEcosystemPhotobacteriumPesticidesbioluminescent assayconjugated enzyme reactionsenzyme inhibition-based assayformulantsluminous bacteriapesticides

Identifiers

PMID36768591
PMCPMC9916951

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.