Evidence map›Paper›PMID 36768751›Full record

ReviewInternational journal of molecular sciences2023

Phytochelatins: Sulfur-Containing Metal(loid)-Chelating Ligands in Plants.

Ilya V Seregin, Anna D Kozhevnikova

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Nickel Toxicity in Plants.International journal of molecular sciences · 2026
    Review
  5. Review
  6. Evaluation of the genes CYPEnvironmental science and pollution research international · 2026
    Article
  7. Review
  8. Augmenting pH Confers toPlants (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Comparative Effects ofInternational journal of molecular sciences · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ilya V SereginK.A. Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya St., 35, 127276 Moscow, Russia.ORCID 0000-0002-4243-9084
Anna D KozhevnikovaK.A. Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya St., 35, 127276 Moscow, Russia.

Funding

Ministry of Science and Higher Education of the Russian Federation 122042700044-6Russian Science Foundation 21-14-00028
6 · The paper itself

Abstract

Phytochelatins (PCs) are small cysteine-rich peptides capable of binding metal(loid)s via SH-groups. Although the biosynthesis of PCs can be induced in vivo by various metal(loid)s, PCs are mainly involved in the detoxification of cadmium and arsenic (III), as well as mercury, zinc, lead, and copper ions, which have high affinities for S-containing ligands. The present review provides a comprehensive account of the recent data on PC biosynthesis, structure, and role in metal(loid) transport and sequestration in the vacuoles of plant cells. A comparative analysis of PC accumulation in hyperaccumulator plants, which accumulate metal(loid)s in their shoots, and in the excluders, which accumulate metal(loid)s in their roots, investigates the question of whether the endogenous PC concentration determines a plant's tolerance to metal(loid)s. Summarizing the available data, it can be concluded that PCs are not involved in metal(loid) hyperaccumulation machinery, though they play a key role in metal(loid) homeostasis. Unraveling the physiological role of metal(loid)-binding ligands is a fundamental problem of modern molecular biology, plant physiology, ionomics, and toxicology, and is important for the development of technologies used in phytoremediation, biofortification, and phytomining.

Indexed as

AminoacyltransferasesPhytochelatinsCadmiumChelating AgentsMetalsPlantsSulfurAminoacyltransferasesCadmiumChelating AgentsMetalsPhytochelatinsSulfurmetal and metalloid accumulation in plantsmetal and metalloid detoxificationmetal and metalloid transportphytochelatinsphytochelatin synthasestress

Identifiers

PMID36768751
PMCPMC9917255

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.