Evidence map›Paper›PMID 36768944›Full record

ReviewInternational journal of molecular sciences2023

Extracellular Vesicle-microRNAs as Diagnostic Biomarkers in Preterm Neonates.

Emily A Schiller, Koral Cohen, Xinhua Lin, Rania El-Khawam, Nazeeh Hanna

Registry-linked trialAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07273643 (Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With Severe Morbidity and Mortality), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07273643 recruitingnot on this mapstarted 2026, after this paper: background citation

Characterization of Extracellular Vesicles From the Cord Blood of Extremely Preterm New Borns and Their Correlation With Severe Morbidity and Mortality

Typeobservational_patient_registrySponsorUniversity Hospital, MontpellierRan2026 to 2027Enrolled30ConditionsIntraventricular Hemorrhage, Pulmonary Hemorrhage, Death, ELGAN (22-28SA)ArmsVenous Cord blood sample, Arterial cord blood sample
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. The emerging role of extracellular vesicles in bronchopulmonary dysplasia.American journal of physiology. Lung cellular and molecular physiology · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emily A SchillerDepartment of Foundational Medicine, New York University Long Island School of Medicine, Mineola, NY 11501, USA.ORCID 0000-0002-1525-8747
Koral CohenDepartment of Foundational Medicine, New York University Long Island School of Medicine, Mineola, NY 11501, USA.
Xinhua LinDepartment of Foundational Medicine, New York University Long Island School of Medicine, Mineola, NY 11501, USA.
Rania El-KhawamDepartment of Pediatrics, Division of Neonatology, New York University Langone Long Island Hospital, Mineola, NY 11501, USA.
Nazeeh HannaDepartment of Foundational Medicine, New York University Long Island School of Medicine, Mineola, NY 11501, USA.ORCID 0000-0003-2167-5712

Funding

Placenta-specific miR-519c-mediated induction of immune tolerance in human placentaR01HD098258 · NICHD · NYU LONG ISLAND SCHOOL OF MEDICINE · PI HANNA, NAZEEH N · 2020 to 2024
$1.8M
NICHD NIH HHS R01 HD098258
6 · The paper itself

Abstract

Neonates born prematurely (<37 weeks of gestation) are at a significantly increased risk of developing inflammatory conditions associated with high mortality rates, including necrotizing enterocolitis, bronchopulmonary dysplasia, and hypoxic-ischemic brain damage. Recently, research has focused on characterizing the content of extracellular vesicles (EVs), particularly microRNAs (miRNAs), for diagnostic use. Here, we describe the most recent work on EVs-miRNAs biomarkers discovery for conditions that commonly affect premature neonates.

Indexed as

Bronchopulmonary DysplasiaExtracellular VesiclesMicroRNAsPregnancy ComplicationsBiomarkersFemaleHumansInfant, NewbornBiomarkersMicroRNAsbiomarkersbronchopulmonary dysplasiaextracellular vesicleshypoxic-ischemic brain damagemiRNAnecrotizing enterocolitisneonateprematurity

Identifiers

PMID36768944
PMCPMC9916767

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.