Evidence map›Paper›PMID 36769045›Full record

ArticleInternational journal of molecular sciences2023

The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes.

Virgilia Sahiri, Jonathan Caron, Elena Roger, Christophe Desterke, Khalil Ghachem, Inna Mohamadou, Justine Serre, Niki Prakoura, Soraya Fellahi, Sandrine Placier and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Virgilia SahiriSorbonne Université, UMR_S 1155, 75006 Paris, France.ORCID 0000-0002-0242-2114
Jonathan CaronSorbonne Université, UMR_S 1155, 75006 Paris, France.
Elena RogerSorbonne Université, UMR_S 1155, 75006 Paris, France.
Christophe DesterkeUniversité Paris-Saclay, Faculté de Médecine, 94270 Le Kremlin-Bicêtre, France.
Khalil GhachemSorbonne Université, UMR_S 1155, 75006 Paris, France.
Inna MohamadouSorbonne Université, UMR_S 1155, 75006 Paris, France.
Justine SerreSorbonne Université, UMR_S 1155, 75006 Paris, France.
Niki PrakouraInstitut National de la Santé et de la Recherche Médicale UMR_S 1155, 75020 Paris, France.
Soraya FellahiInserm UMR_S 938, Centre de Recherche Saint-Antoine, Institut Hospitalo-Universitaire de Cardio-Métabolisme et Nutrition (ICAN), Sorbonne Université, 75013 Paris, France.
Sandrine PlacierSorbonne Université, UMR_S 1155, 75006 Paris, France.
Sahil AdriouchUNIROUEN, INSERM, U1234, Pathophysiology, Autoimmunity, Neuromuscular Diseases and Regenerative THERapies (PANTHER), Normandie University, 76000 Rouen, France.ORCID 0000-0002-0265-7773
Lu ZhangDivision of Nephrology, Affiliated Hospital of Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, Nanjing 210004, China.
Christos E ChadjichristosSorbonne Université, UMR_S 1155, 75006 Paris, France.ORCID 0000-0001-6657-7900
Christos ChatziantoniouSorbonne Université, UMR_S 1155, 75006 Paris, France.
Hans Kristian LorenzoUniversité Paris Saclay, INSERM UA/09 UMR-S 935, 94800 Villejuif, France.
Jean-Jacques BoffaSorbonne Université, UMR_S 1155, 75006 Paris, France.
Inserm · FRNanjing University of Chinese Medicine · CN

Funding

Annual funding of Inserm, Sorbonne Université NAAssistance Publique - Hôpitaux de Paris AORC17Fondation du Rein", France, RAD16099LLAPhD grant from the Ministry of Education and Scientific Research of Ivory Coast. NA
6 · The paper itself

Abstract

Focal segmental glomerulosclerosis (FSGS) is a major cause of end-stage renal disease and remains without specific treatment. To identify new events during FSGS progression, we used an experimental model of FSGS associated with nephroangiosclerosis in rats injected with L-NAME (N

Indexed as

Glomerulosclerosis, Focal SegmentalPodocytesAngiogenesis InhibitorsAnimalsCaspasesDisease Models, AnimalHumansNG-Nitroarginine Methyl EsterProteinuriaRatsThrombospondinsAngiogenesis InhibitorsCaspasesISM1 protein, humanNG-Nitroarginine Methyl EsterThrombospondinsapoptosischronic kidney disease progressionFSGSglomerular diseasespodocytesproteinuria

Identifiers

PMID36769045
PMCPMC9916724
OpenAlexW4318779462

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.