Evidence map›Paper›PMID 36769823›Full record

ArticleJournal of clinical medicine2023

Tinnitus and Its Relation to Depression, Anxiety, and Stress-A Population-Based Cohort Study.

Berit Hackenberg, Julia Döge, Karoline O'Brien, Andrea Bohnert, Karl J Lackner, Manfred E Beutel, Matthias Michal, Thomas Münzel, Philipp S Wild, Norbert Pfeiffer and 4 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A Systematic Review on the Genetic Contribution to Tinnitus.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Pooled it
  5. Trial
  6. Article
  7. Article
  8. Article
  9. A discrete serotonergic circuit involved in the generation of tinnitus behavior.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Observational
  15. Article
  16. Article
  17. Tinnitus is not associated with cardiovascular risk factors or mortality in the Gutenberg Health Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Berit HackenbergDepartment of Otorhinolaryngology, University Medical Center Mainz, 55131 Mainz, Germany.
Julia DögeDepartment of Otorhinolaryngology, University Medical Center Mainz, 55131 Mainz, Germany.
Karoline O'BrienDepartment of Otorhinolaryngology, University Medical Center Mainz, 55131 Mainz, Germany.
Andrea BohnertDepartment of Otorhinolaryngology, University Medical Center Mainz, 55131 Mainz, Germany.
Karl J LacknerInstitute for Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, 55131 Mainz, Germany.
Manfred E BeutelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, 55131 Mainz, Germany.
Matthias MichalDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0002-4028-5851
Thomas MünzelDepartment of Cardiology-Cardiology I, University Medical Center Mainz, 55131 Mainz, Germany.
Philipp S WildPreventive Cardiology and Preventive Medicine-Department of Cardiology, University Medical Center Mainz, 55131 Mainz, Germany.
Norbert PfeifferDepartment of Ophthalmology, University Medical Center Mainz, 55131 Mainz, Germany.
Andreas SchulzPreventive Cardiology and Preventive Medicine-Department of Cardiology, University Medical Center Mainz, 55131 Mainz, Germany.
Irene SchmidtmannInstitute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Mainz, 55131 Mainz, Germany.
Christoph MatthiasDepartment of Otorhinolaryngology, University Medical Center Mainz, 55131 Mainz, Germany.
Katharina BahrDepartment of Otorhinolaryngology, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7428-127X

Funding

Boehringer Ingelheim Fonds Boehringer IngelheimFederal Ministry of Education and Research BMBF 01EO1503Johannes Gutenberg University of Mainz Center for Translational Vascular Biology (CTVB)Johannes Gutenberg University of Mainz Wissen schafft ZukunftPHILIPS Medical Systems PHILIPS Medical SystemsStiftung Rheinland-Pfalz für Innovation AZ 961-386261/733
6 · The paper itself

Abstract

Tinnitus is a common symptom reported in otolaryngologic practice. Although the pathophysiology of tinnitus has not been fully understood, clinical studies suggest that psychological symptoms of depression, anxiety, and somatization are increased in tinnitus patients. However, patients seeking medical treatment for tinnitus may be especially vulnerable. Population-based studies reporting on the association between tinnitus and psychological distress are still lacking. The aim of this study was to investigate the correlation of tinnitus with depression, anxiety, or somatization in a large population-based cohort. The Gutenberg Health Study is a population-based cohort study. Participants were asked about the occurrence of tinnitus (yes/no) and how much they were bothered by it. In addition, they completed the PHQ-9, GAD-7, and SSS-8 questionnaires to assess depressive symptoms, anxiety, and somatic symptom disorders. A total of 8539 participants were included in the study cohort. Tinnitus prevalence was 28.0% (2387). The prevalence of depression/anxiety/somatic symptom disorders was significantly higher among participants with tinnitus than among participants without tinnitus (7.9%/5.4%/40.4% participants with tinnitus vs. 4.6%/3.3%/26.9% participants without tinnitus,

Indexed as

anxietycohort studydepressiontinnitus

Identifiers

PMID36769823
PMCPMC9917824

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.