Evidence map›Paper›PMID 36770729›Full record

ArticleMolecules (Basel, Switzerland)2023

Generation of Aurachin Derivatives by Whole-Cell Biotransformation and Evaluation of Their Antiprotozoal Properties.

Sebastian Kruth, Cindy J-M Zimmermann, Katharina Kuhr, Wolf Hiller, Stephan Lütz, Jörg Pietruszka, Marcel Kaiser, Markus Nett

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Highly Selective Electrosynthesis of 1Organic process research & development · 2024
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sebastian KruthLaboratory of Technical Biology, Department of Biochemical and Chemical Engineering, TU Dortmund University, 44227 Dortmund, Germany.
Cindy J-M ZimmermannInstitute of Bioorganic Chemistry, Heinrich Heine University Düsseldorf at Forschungszentrum Jülich and Bioeconomy Science Center (BioSC), 52426 Jülich, Germany.
Katharina KuhrLaboratory of Technical Biology, Department of Biochemical and Chemical Engineering, TU Dortmund University, 44227 Dortmund, Germany.
Wolf HillerNMR Laboratory, Department of Chemistry and Chemical Biology, TU Dortmund University, 44227 Dortmund, Germany.
Stephan LützLaboratory of Bioprocess Engineering, Department of Biochemical and Chemical Engineering, TU Dortmund University, 44227 Dortmund, Germany.ORCID 0000-0001-8534-0554
Jörg PietruszkaInstitute of Bioorganic Chemistry, Heinrich Heine University Düsseldorf at Forschungszentrum Jülich and Bioeconomy Science Center (BioSC), 52426 Jülich, Germany.ORCID 0000-0002-9819-889X
Marcel KaiserSwiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland.ORCID 0000-0003-1785-7302
Markus NettLaboratory of Technical Biology, Department of Biochemical and Chemical Engineering, TU Dortmund University, 44227 Dortmund, Germany.ORCID 0000-0003-0847-086X

Funding

Deutsche Forschungsgemeinschaft 445751305European Regional Development Fund EFRE-0300098
6 · The paper itself

Abstract

The natural product aurachin D is a farnesylated quinolone alkaloid, which is known to possess activity against the causative agent of malaria,

Indexed as

Antiprotozoal AgentsBiological ProductsChagas DiseaseLeishmania donovaniQuinolonesTrypanosoma cruziBiotransformationEscherichia coliHumansParasitic Sensitivity TestsPlasmodium falciparumAntiprotozoal AgentsBiological ProductsQuinolonesantiprotozoalaurachinbiotransformationEscherichia coliquinolinequinolone

Identifiers

PMID36770729
PMCPMC9919615

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.