Evidence map›Paper›PMID 36770865›Full record

ArticleMolecules (Basel, Switzerland)2023

Hyperpolarizing DNA Nucleobases via NMR Signal Amplification by Reversible Exchange.

Bryce E Kidd, Max E Gemeinhardt, Jamil A Mashni, Jonathan L Gesiorski, Liana B Bales, Miranda N Limbach, Roman V Shchepin, Kirill V Kovtunov, Igor V Koptyug, Eduard Y Chekmenev and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The journal of physical chemistry. B · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bryce E KiddSchool of Chemical & Biomolecular Sciences, Southern Illinois University, Carbondale, IL 62901, USA.
Max E GemeinhardtSchool of Chemical & Biomolecular Sciences, Southern Illinois University, Carbondale, IL 62901, USA.
Jamil A MashniSchool of Chemical & Biomolecular Sciences, Southern Illinois University, Carbondale, IL 62901, USA.
Jonathan L GesiorskiSchool of Chemical & Biomolecular Sciences, Southern Illinois University, Carbondale, IL 62901, USA.
Liana B BalesSchool of Chemical & Biomolecular Sciences, Southern Illinois University, Carbondale, IL 62901, USA.
Miranda N LimbachSchool of Chemical & Biomolecular Sciences, Southern Illinois University, Carbondale, IL 62901, USA.ORCID 0000-0003-4266-7279
Roman V ShchepinDepartment of Chemistry, Biology, and Health Sciences, South Dakota School of Mines & Technology, Rapid City, SD 57701, USA.ORCID 0000-0001-9135-3036
Kirill V KovtunovInternational Tomography Center SB RAS, 3A Institutskaya St., Novosibirsk 630090, Russia.
Igor V KoptyugInternational Tomography Center SB RAS, 3A Institutskaya St., Novosibirsk 630090, Russia.
Eduard Y ChekmenevDepartment of Chemistry, Integrative Biosciences (Ibio), Karmanos Cancer Institute (KCI) Wayne State University, Detroit, MI 48202, USA.ORCID 0000-0002-8745-8801
Boyd M GoodsonSchool of Chemical & Biomolecular Sciences, Southern Illinois University, Carbondale, IL 62901, USA.ORCID 0000-0001-6079-5077

Funding

National Science Foundation CHE-1905341, CHE-1904780, CHE-1416432, DMR-1757954, DMR-2150489Russian Science Foundation grant #22-43-04426
6 · The paper itself

Abstract

The present work investigates the potential for enhancing the NMR signals of DNA nucleobases by parahydrogen-based hyperpolarization. Signal amplification by reversible exchange (SABRE) and SABRE in Shield Enables Alignment Transfer to Heteronuclei (SABRE-SHEATH) of selected DNA nucleobases is demonstrated with the enhancement (

Indexed as

ImidazolesMagnetic Resonance ImagingDNAMagnetic Resonance SpectroscopyNitrogen IsotopesDNAImidazolesNitrogen IsotopeshyperpolarizationNMR & MRInucleic acidsPHIPSABRE

Identifiers

PMID36770865
PMCPMC9921525

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.