Evidence map›Paper›PMID 36770997›Full record

ArticleMolecules (Basel, Switzerland)2023

Autoantibody-Abzymes with Catalase Activity in Experimental Autoimmune Encephalomyelitis Mice.

Andrey E Urusov, Anna S Tolmacheva, Kseniya S Aulova, Georgy A Nevinsky

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Oxidative Stress Markers in Multiple Sclerosis.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Catalase Activity of IgGs of Patients Infected with SARS-CoV-2.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrey E UrusovInstitute of Chemical Biology and Fundamental Medicine, SB of the Russian Academy of Sciences, Lavrentiev Ave., 8, Novosibirsk 630090, Russia.
Anna S TolmachevaInstitute of Chemical Biology and Fundamental Medicine, SB of the Russian Academy of Sciences, Lavrentiev Ave., 8, Novosibirsk 630090, Russia.
Kseniya S AulovaInstitute of Chemical Biology and Fundamental Medicine, SB of the Russian Academy of Sciences, Lavrentiev Ave., 8, Novosibirsk 630090, Russia.ORCID 0000-0001-6972-9068
Georgy A NevinskyInstitute of Chemical Biology and Fundamental Medicine, SB of the Russian Academy of Sciences, Lavrentiev Ave., 8, Novosibirsk 630090, Russia.ORCID 0000-0002-4988-8923
Institute of Chemical Biology and Fundamental Medicine · RU

Funding

Russian Science Foundation 22-15-00103
6 · The paper itself

Abstract

The exact mechanisms of the evolution of multiple sclerosis are still unknown. At the same time, the development in C57BL/6 mice of experimental autoimmune encephalomyelitis (EAE, simulating human multiple sclerosis) happens as a result of the violation of bone marrow hematopoietic stem cell differentiation profiles integrated with the production of toxic auto-antibodies splitting the basic myelin protein, myelin oligodendrocyte glycoprotein (MOG), histones, and DNA. It has been shown that IgGs from the plasma of healthy humans and autoimmune patients oxidize many different compounds due to their peroxidase (H

Indexed as

Antibodies, CatalyticEncephalomyelitis, Autoimmune, ExperimentalMultiple SclerosisAnimalsAutoantibodiesCatalaseDNAHistonesHumansHydrogen PeroxideMiceMice, Inbred C57BLMyelin-Oligodendrocyte GlycoproteinAntibodies, CatalyticAutoantibodiesCatalaseDNAHistonesHydrogen PeroxideMyelin-Oligodendrocyte GlycoproteinC57BL/6 micecatalase activitycatalytic antibodiesEAE model

Identifiers

PMID36770997
PMCPMC9921166
OpenAlexW4318480012

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.