Evidence map›Paper›PMID 36771260›Full record

ArticleNutrients2023

Improved HDL Cholesterol through Vitamin D Status Correction Substantially Lowers 10-Year Atherosclerotic Cardiovascular Disease Risk Score in Vitamin D-Deficient Arab Adults.

Shaun Sabico, Kaiser Wani, William B Grant, Nasser M Al-Daghri

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  6. Review
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  12. Evaluation of the vitamin D response index in a Saudi cohort.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  13. Review
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Shaun SabicoBiochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-5248-2350
Kaiser WaniBiochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-9568-6516
William B GrantSunlight, Nutrition and Health Research Center, P.O. Box 641603, San Francisco, CA 94164-1603, USA.ORCID 0000-0002-1439-3285
Nasser M Al-DaghriBiochemistry Department, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-5472-1725
King Saud University · SASunlight Nutrition and Health Research Center · US

Funding

Deputyship for Research and Innovation, Ministry of Education in Saudi Arabia IFKSURG-2-27
6 · The paper itself

Abstract

This interventional study aimed to determine whether correcting vitamin D status in deficient Arab adults [25(OH)D <50 nmol/L] improves their 10-year risk of Atherosclerotic Cardiovascular Disease (ASCVD) risk scores. Saudi adults (58 males 62 females) with baseline vitamin D deficiency (<50 nmol/L) were given 50,000 IU cholecalciferol weekly for 2 months, then twice a month, followed by daily 1000 IU until month 6. Fasting blood samples were collected pre- and post-intervention and assessed for glucose, lipids, and 25(OH)D levels. The predicted 10-year ASCVD risk scores were calculated at baseline and after intervention. At baseline, significantly higher 10-year ASCDV risk scores were observed in males than females (9% vs. 3%,

Indexed as

Cardiovascular DiseasesVitamin D DeficiencyAdultArabsCholecalciferolCholesterol, HDLFemaleGlucoseHumansMaleRisk FactorsVitamin DVitaminsCholecalciferolCholesterol, HDLGlucoseVitamin DVitaminsASCVD risk scorecardiovascular diseaseHDL cholesterollipidssex specificvitamin D correction

Identifiers

PMID36771260
PMCPMC9921125
OpenAlexW4317733586

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.