Evidence map›Paper›PMID 36771313›Full record

ReviewNutrients2023

Inflammatory Response: A Crucial Way for Gut Microbes to Regulate Cardiovascular Diseases.

Wen Wang, Luo-Jiang Zhu, Yue-Qi Leng, Yu-Wan Wang, Te Shi, Wei-Zhong Wang, Jia-Cen Sun

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Article
  7. Review
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  11. Article
  12. Article
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  15. Review
  16. Impact ofFrontiers in gastroenterology (Lausanne, Switzerland) · 2024
    Review
  17. Article
  18. Review
  19. Review
  20. Benefits of Biotics for Cardiovascular Diseases.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wen WangDepartment of Marine Biomedicine and Polar Medicine, Naval Medical Center, Naval Medical University, Shanghai 200433, China.ORCID 0000-0001-6008-1074
Luo-Jiang ZhuDepartment of Neurosurgery, 922th Hospital of PLA, Hengyang 421000, China.ORCID 0000-0001-8209-735X
Yue-Qi LengDepartment of Marine Biomedicine and Polar Medicine, Naval Medical Center, Naval Medical University, Shanghai 200433, China.
Yu-Wan WangDepartment of Marine Biomedicine and Polar Medicine, Naval Medical Center, Naval Medical University, Shanghai 200433, China.
Te ShiDepartment of Gastroenterology, Naval Medical Center, Naval Medical University, Shanghai 200433, China.
Wei-Zhong WangDepartment of Marine Biomedicine and Polar Medicine, Naval Medical Center, Naval Medical University, Shanghai 200433, China.ORCID 0000-0001-6979-4505
Jia-Cen SunDepartment of Marine Biomedicine and Polar Medicine, Naval Medical Center, Naval Medical University, Shanghai 200433, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota is the largest and most complex microflora in the human body, which plays a crucial role in human health and disease. Over the past 20 years, the bidirectional communication between gut microbiota and extra-intestinal organs has been extensively studied. A better comprehension of the alternative mechanisms for physiological and pathophysiological processes could pave the way for health. Cardiovascular disease (CVD) is one of the most common diseases that seriously threatens human health. Although previous studies have shown that cardiovascular diseases, such as heart failure, hypertension, and coronary atherosclerosis, are closely related to gut microbiota, limited understanding of the complex pathogenesis leads to poor effectiveness of clinical treatment. Dysregulation of inflammation always accounts for the damaged gastrointestinal function and deranged interaction with the cardiovascular system. This review focuses on the characteristics of gut microbiota in CVD and the significance of inflammation regulation during the whole process. In addition, strategies to prevent and treat CVD through proper regulation of gut microbiota and its metabolites are also discussed.

Indexed as

Cardiovascular DiseasesGastrointestinal MicrobiomeHypertensionProbioticsHumansInflammationPrebioticsPrebioticscardiovascular diseasegut microbiotainflammatory responsemetaboliteprebiotics and probiotics

Identifiers

PMID36771313
PMCPMC9921390
OpenAlexW4317932324

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.