ArticleAnnals of medicine2023
Chronic disease clusters are associated with prolonged, bothersome, and multisite musculoskeletal pain: a population-based study on Northern Finns.
Article in Annals of medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- The role of co-occurring obesity in the association between lumbar disc degeneration and disability related to low back pain.BMC musculoskeletal disorders · 2026Article
- Musculoskeletal Pain, Insomnia and Health-Related Quality of Life: Associations in the Middle-Aged General Population.European journal of pain (London, England) · 2026Article
- Chronic disease clusters and health-related quality of life among individuals with musculoskeletal pain: a Northern Finland Birth Cohort 1966 study.Family practice · 2025Article
- Beyond pain intensity: Validating single-item pain bothersomeness measures.The journal of pain · 2025Article
- Exploring the association of metabolic factors and chronic musculoskeletal pain over a period of 10 years - the Doetinchem Cohort Study.Clinical rheumatology · 2025Article
- The relationship between chronic pain and health-related quality of life: the mediating roles of frailty and depression in chronic disease patients.Frontiers in public health · 2025Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic diseases often accumulate with musculoskeletal (MSK) pain. However, less evidence is available on idiosyncratic patterns of chronic diseases and their relationships with the severity of MSK pain in general MSK pain populations. MATERIAL AND
methodsQuestionnaire-based data on physician-diagnosed chronic diseases, MSK pain and its dimensions (frequency, intensity, bothersomeness, and the number of pain sites), and confounders were collected from the Northern Finland Birth Cohort 1966 at the age of 46. Latent Class Analysis (LCA) was used to identify chronic disease clusters among individuals who reported any MSK pain within the previous year (
resultsLCA resulted in three clusters:
conclusionsDistinct patterns of chronic disease accumulation can be identified in the general MSK pain population. It seems that mental and metabolic health are at interplay with severe MSK pain. These findings suggest a potential need to screen for psychiatric and metabolic entities of health when treating working-aged people with MSK pain.Key messagesThis large study on middle-aged people with musculoskeletal pain aimed to examine the idiosyncratic patterns of chronic diseases and their relationships with the severity of musculoskeletal pain. Latent class cluster analysis identified three chronic disease clusters:
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Registered trials
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