Evidence map›Paper›PMID 36773564›Full record

ArticleEnvironment international2023

Air pollution and plasma amyloid beta in a cohort of older adults: Evidence from the Ginkgo Evaluation of Memory study.

Anjum Hajat, Christina Park, Claire Adam, Annette L Fitzpatrick, Sindana D Ilango, Cindy Leary, Tanya Libby, Oscar Lopez, Erin O Semmens, Joel D Kaufman

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. 2-aminobutyrate mediates the impact of air pollution on blood biomarkers of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Association between chronic PMBMC public health · 2025
    Article
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  15. Association of PMNeurology · 2024
    Article
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  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Anjum HajatUniversity of Washington, Department of Epidemiology, 3980 15th Ave NE, Seattle, WA 98195, USA. Electronic address: anjumh@uw.edu.
Christina ParkUniversity of Washington, Department of Epidemiology, 3980 15th Ave NE, Seattle, WA 98195, USA.
Claire AdamUniversity of Montana, School of Public and Community Health Sciences, Skaggs Building, 32 Campus Drive Missola, MT 59812, USA.
Annette L FitzpatrickUniversity of Washington, Department of Family Medicine, 4225 Roosevelt Ave NE Seattle, WA 98195, USA.
Sindana D IlangoUniversity of Washington, Department of Epidemiology, 3980 15th Ave NE, Seattle, WA 98195, USA.
Cindy LearyUniversity of Montana, School of Public and Community Health Sciences, Skaggs Building, 32 Campus Drive Missola, MT 59812, USA.
Tanya LibbyUniversity of Washington, Department of Epidemiology, 3980 15th Ave NE, Seattle, WA 98195, USA.
Oscar LopezUniversity of Pittsburgh, Department of Neurology, 811 Kaufmann Medical Building, 3471 Fifth Avenue, Pittsburgh, PA 15123, USA.
Erin O SemmensUniversity of Montana, School of Public and Community Health Sciences, Skaggs Building, 32 Campus Drive Missola, MT 59812, USA.
Joel D KaufmanUniversity of Washington, Department of Environmental and Occupational Health and Epidemiology, 4225 Roosevelt Ave NE, Seattle, WA 98195, USA.
University of Washington · USUniversity of Montana · USUniversity of Pittsburgh · US

Funding

TREATMENT OF DEPRESSION IN ALZHEIMER'S DISEASEP50AG005133 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SWEET, ROBERT A · 1985 to 2019
$43.0M
XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Nicole Ann Errett · 1995 to 2026
$42.5M
GINKGO BILOBA PREVENTION TRIAL IN OLDER INDIVIDUALSU01AT000162 · NCCIH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOPEZ, OSCAR L. · 1999 to 2009
$34.7M
Research Education ComponentP30AG066468 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI C. Elizabeth Shaaban · 2020 to 2026
$29.4M
Wildfires and Cardiovascular Health: Evaluating Associations and Intervention StrategiesP20GM130418 · NIGMS · UNIVERSITY OF MONTANA · PI Maja Pedersen · 2020 to 2026
$17.9M
Biostatistics, Epidemiologic & Bioinformatic Training in Environmental HealthT32ES015459 · NIEHS · UNIVERSITY OF WASHINGTON · PI June T. Spector · 2009 to 2026
$10.6M
Air pollution, the social environment, and Alzheimer's disease: Risk and resilience in the Ginkgo Evaluation Memory StudyRF1AG057033 · NIA · UNIVERSITY OF WASHINGTON · PI FITZPATRICK, ANNETTE L., KAUFMAN, JOEL DANIEL · 2017 to 2017
$2.3M
EPA RD838300NCCIH NIH HHS U01 AT000162NIA NIH HHS P30 AG066468NIA NIH HHS P50 AG005133NIA NIH HHS RF1 AG057033NIEHS NIH HHS P30 ES007033NIEHS NIH HHS T32 ES015459NIGMS NIH HHS P20 GM130418
6 · The paper itself

Abstract

Air pollution has been linked to Alzheimer's disease and related dementias (ADRD), but the mechanisms connecting air pollution to ADRD have not been firmly established. Air pollution may cause oxidative stress and neuroinflammation and contribute to the deposition of amyloid beta (Aβ) in the brain. We examined the association between fine particulate matter<2.5 μm in diameter (PM

Indexed as

Air PollutantsAir PollutionAgedAmyloid beta-PeptidesCross-Sectional StudiesEnvironmental ExposureGinkgo bilobaHumansNitrogen DioxideParticulate MatterAir PollutantsAmyloid beta-PeptidesNitrogen DioxideParticulate MatterAgingAir pollutionAlzheimer’s diseaseAmyloid betaBiomarkersDementia

Identifiers

PMID36773564
PMCPMC9974914
OpenAlexW4319071953

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.