Evidence map›Paper›PMID 36778471›Full record

ArticleResearch square2023

Flavones provide resistance to DUX4-induced toxicity via an mTor-independent mechanism.

Justin Cohen, Shushu Huang, Katherine Koczwara, Vincent Ho, Keryn Woodman, Angela Lek, Jack Arbiser, Monkol Lek, Alec DeSimone

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Justin CohenYale School of Medicine.
Shushu HuangYale School of Medicine.
Katherine KoczwaraYale School of Medicine.
Vincent HoYale School of Medicine.
Keryn WoodmanYale School of Medicine.
Angela LekYale School of Medicine.
Jack ArbiserEmory University.ORCID 0000-0002-6798-6383
Monkol LekYale School of Medicine.
Alec DeSimoneYale School of Medicine.ORCID 0000-0001-9961-9839
Emory University · USYale University · US

Funding

Training Core [Parent Title: NOVEL THERAPEUTICS FOR FSHD]P50HD060848 · NICHD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI EMERSON, CHARLES P. · 2018 to 2023
$8.6M
NICHD NIH HHS P50 HD060848
6 · The paper itself

Abstract

Facioscapulohumeral muscular dystrophy (FSHD) is among the most common of the muscular dystrophies, affecting nearly 1 in 8000 individuals, and is a cause of profound disability. Genetically, FSHD is linked to the contraction and/or epigenetic de-repression of the

Identifiers

PMID36778471
PMCPMC9915774
OpenAlexW4318948331

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.