Evidence map›Paper›PMID 36779063›Full record

ArticleFrontiers in neurology2023

Identifying vulnerable plaques: A 3D carotid plaque radiomics model based on HRMRI.

Xun Zhang, Zhaohui Hua, Rui Chen, Zhouyang Jiao, Jintao Shan, Chong Li, Zhen Li

Abstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  9. Quality assessment of radiomics models in carotid plaque: a systematic review.Quantitative imaging in medicine and surgery · 2024
    Review
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  13. A radiomics-based approach with automated segmentation for identifying symptomatic basilar artery plaques in acute stroke.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xun ZhangDepartment of Endovascular Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Zhaohui HuaDepartment of Endovascular Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Rui ChenDepartment of Magnetic Resonance Imaging, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Zhouyang JiaoDepartment of Endovascular Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Jintao ShanDepartment of Endovascular Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Chong LiDivision of Vascular Surgery, New York University Medical Center, New York, NY, United States.
Zhen LiDepartment of Endovascular Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Identification of vulnerable carotid plaque is important for the treatment and prevention of stroke. In previous studies, plaque vulnerability was assessed qualitatively. We aimed to develop a 3D carotid plaque radiomics model based on high-resolution magnetic resonance imaging (HRMRI) to quantitatively identify vulnerable plaques. Methods: Ninety patients with carotid atherosclerosis who underwent HRMRI were randomized into training and test cohorts. Using the radiological characteristics of carotid plaques, a traditional model was constructed. A 3D carotid plaque radiomics model was constructed using the radiomics features of 3D T Results: 48 patients (53.33%) were symptomatic and 42 (46.67%) were asymptomatic. The traditional model was constructed using intraplaque hemorrhage, plaque enhancement, wall remodeling pattern, and lumen stenosis, and it provided an area under the curve (AUC) of 0.816 vs. 0.778 in the training and testing sets. In the two cohorts, the 3D carotid plaque radiomics model and the combined model had an AUC of 0.915 vs. 0.835 and 0.957 vs. 0.864, respectively. In the training set, both the radiomics model and the combination model outperformed the traditional model, but there was no significant difference between the radiomics model and the combined model. Conclusions: HRMRI-based 3D carotid radiomics models can improve the precision of detecting vulnerable carotid plaques, consequently improving risk classification and clinical decision-making in patients with carotid stenosis.

Indexed as

3D reconstructioncarotid atherosclerosis (AS)high-resolution magnetic resonance imagingradiomicsstrokevulnerable plaque

Identifiers

PMID36779063
PMCPMC9908750

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.