Evidence map›Paper›PMID 36780522›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Helminth egg derivatives as proregenerative immunotherapies.

David R Maestas, Liam Chung, Jin Han, Xiaokun Wang, Sven D Sommerfeld, Sean H Kelly, Erika Moore, Helen Hieu Nguyen, Joscelyn C Mejías, Alexis N Peña and 19 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  4. Review
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  7. Clinical & translational immunology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 2 institutions in 1 country.

David R MaestasTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.ORCID 0000-0002-8207-1835
Liam ChungTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Jin HanTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Xiaokun WangTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Sven D SommerfeldTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Sean H KellyTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.ORCID 0000-0001-8590-3839
Erika MooreTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.ORCID 0000-0003-2192-6147
Helen Hieu NguyenTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.ORCID 0000-0001-8015-5296
Joscelyn C MejíasTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Alexis N PeñaTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Hong ZhangTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Joshua S T HooksTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Alexander F ChinTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
James I AndorkoTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Cynthia A BerlinickeTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Kavita KrishnanTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.ORCID 0000-0003-1345-0249
Younghwan ChoiTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Amy E AndersonTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.ORCID 0000-0003-3328-0523
Ronak MahatmeTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.ORCID 0000-0001-8730-221X
Christopher MejiaTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Marie EricTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
JiWon WooTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.ORCID 0000-0001-9448-9051
Sudipto GangulyBloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, School of Medicine, Baltimore, MD 21287.
Donald J ZackDepartment of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287.ORCID 0000-0002-7966-1973
Liang ZhaoBloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, School of Medicine, Baltimore, MD 21287.ORCID 0000-0002-2126-6778
Edward J PearceBloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, School of Medicine, Baltimore, MD 21287.
Franck HousseauBloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, School of Medicine, Baltimore, MD 21287.ORCID 0000-0002-7028-3953
Drew M PardollBloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, School of Medicine, Baltimore, MD 21287.
Jennifer H ElisseeffTranslational Tissue Engineering Center, Johns Hopkins University, Baltimore, MD 21287.
Johns Hopkins University · USBloomberg (United States) · US

Funding

Biomaterials-directed regenerative immunotherapiesDP1AR076959 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI ELISSEEFF, JENNIFER H · 2019 to 2023
$5.7M
Together: Transforming and Translating Discovery to Improve HealthKL2TR001429 · NCATS · UNIVERSITY OF FLORIDA · PI GUIRGIS, FAHEEM W, LEEUWENBURGH, CHRISTIAAN · 2015 to 2023
$5.5M
Translational Aging Research Training ProgramT32AG058527 · NIA · JOHNS HOPKINS UNIVERSITY · PI Peter M. Abadir, Esther Seunghee Oh · 2018 to 2026
$4.0M
T32: Predoctoral and Postdoctoral Training Program in Nanotechnology for Cancer ResearchT32CA153952 · NCI · JOHNS HOPKINS UNIVERSITY · PI Denis Wirtz · 2015 to 2026
$3.5M
Statistical optimization of self-assembled biosynthetic cornea implantsR01EY029055 · NEI · JOHNS HOPKINS UNIVERSITY · PI ELISSEEFF, JENNIFER H · 2018 to 2021
$1.8M
NCATS NIH HHS KL2 TR001429NCI NIH HHS T32 CA153952NEI NIH HHS R01 EY029055NIAID NIH HHS HHSN272201700014CNIAMS NIH HHS DP1 AR076959NIA NIH HHS T32 AG058527
6 · The paper itself

Abstract

The immune system is increasingly recognized as an important regulator of tissue repair. We developed a regenerative immunotherapy from the helminth

Indexed as

Schistosomiasis mansoniAnimalsAntigens, HelminthCytokinesImmunotherapyMiceSchistosoma mansoniT-Lymphocytes, Helper-InducerAntigens, HelminthCytokinesbiomaterialshelminthimmune responseregenerative medicinetissue engineering

Identifiers

PMID36780522
PMCPMC9974432
OpenAlexW4320483814

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.