Evidence map›Paper›PMID 36780841›Full record

ArticleEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology2023

In vivo serotonin transporter and 1A receptor binding potential and ecological momentary assessment (EMA) of stress in major depression and suicidal behavior.

Elizabeth A Bartlett, Francesca Zanderigo, Barbara Stanley, Tse-Hwei Choo, Hanga C Galfalvy, Spiro P Pantazatos, M Elizabeth Sublette, Jeffrey M Miller, Maria A Oquendo, J John Mann

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Let's Move Towards Precision Suicidology.Current psychiatry reports · 2025
    Review
  4. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Elizabeth A BartlettMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA. Electronic address: eab2266@cumc.columbia.edu.
Francesca ZanderigoMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA.
Barbara StanleyMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA.
Tse-Hwei ChooMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA.
Hanga C GalfalvyMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA.
Spiro P PantazatosMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA.
M Elizabeth SubletteMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA.
Jeffrey M MillerMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA.
Maria A OquendoDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
J John MannMolecular Imaging and Neuropathology Area, New York State Psychiatric Institute, New York, USA; Department of Psychiatry, Columbia University Irving Medical Center, New York, USA; Department of Radiology, Columbia University Irving Medical Center, New York, USA.
Columbia University Irving Medical Center · USUniversity of Pennsylvania · US

Funding

Suicidal Behavior: Aggression Subtypes, Childhood Adversity and Stress ResponseP50MH090964 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI MANN, JOSEPH JOHN · 2013 to 2022
$23.6M
Research Training in Mood and Anxiety Disorders: From Animal Models to PatientsT32MH015144 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Eduardo David Leonardo · 1985 to 2026
$11.1M
Neurobiological Underpinnings of Two Suicidal SubtypesR01MH109326 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MANN, JOSEPH JOHN, OQUENDO, MARIA A · 2016 to 2020
$2.4M
PET imaging of dynorphin/kappa-opioid reactivity to stress in depressionK01MH129780 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Elizabeth Adams Bartlett · 2022 to 2026
$544k
NIMH NIH HHS K01 MH129780NIMH NIH HHS P50 MH090964NIMH NIH HHS R01 MH109326NIMH NIH HHS T32 MH015144
6 · The paper itself

Abstract

We examined relationships between the serotonin system and stress in major depression and suicidal behavior. Twenty-five medication-free depressed participants (13 suicide attempters) underwent same-day [

Indexed as

Major Depressive DisorderBiomarkersBrainDepressionEcological Momentary AssessmentHumansPositron-Emission TomographyReceptor, Serotonin, 5-HT1ASerotoninSerotonin Plasma Membrane Transport ProteinsSuicidal IdeationBiomarkersReceptor, Serotonin, 5-HT1ASerotoninSerotonin Plasma Membrane Transport Proteinscurrent stressecological momentary assessmentmajor depressionserotonin 1A receptorSerotonin transportersuicidal behavior

Identifiers

PMID36780841
PMCPMC10121874
OpenAlexW4320085779

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.