Evidence map›Paper›PMID 36785530›Full record

ArticleDrug delivery2023

Investigating the self-assembling of nicotinic hydrazide-based amphiphile into nano-range vesicles and its amphotericin B loading applications.

Kashif Hussain, Abdul Jabbar, Khwaja Ali Hasan, Muneeb Ali, Zaheer Ul-Haq, Muhammad Raza Shah, Saeed Ahmad Khan, Md Abdur Rashid, Mohsin Kazi, Muhammad Naseer Abbas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 10 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Kashif HussainH.E.J. Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, Karachi University, Karachi, Pakistan.
Abdul JabbarH.E.J. Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, Karachi University, Karachi, Pakistan.
Khwaja Ali HasanMolecular Biology & Structural Biochemistry Research Laboratory, Department of Biochemistry, University of Karachi, Karachi, Pakistan.
Muneeb AliH.E.J. Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, Karachi University, Karachi, Pakistan.
Zaheer Ul-HaqH.E.J. Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, Karachi University, Karachi, Pakistan.ORCID 0000-0002-8530-8711
Muhammad Raza ShahH.E.J. Research Institute of Chemistry, International Centre for Chemical and Biological Sciences, Karachi University, Karachi, Pakistan.
Saeed Ahmad KhanDepartment of Pharmacy, Kohat University of Science and Technology, Kohat, Pakistan.
Md Abdur RashidPharmacy Discipline, Faculty of Health, School of Clinical Sciences, Queensland University of Technology, Brisbane, Queensland, Australia.ORCID 0000-0001-9404-5186
Mohsin KaziDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.ORCID 0000-0002-5611-0378
Muhammad Naseer AbbasDepartment of Pharmacy, Kohat University of Science and Technology, Kohat, Khyber Pakhtunkhwa, Pakistan.
University of Karachi · PKKohat University of Science and Technology · PKKing Saud University · SAQueensland University of Technology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most of the drugs are hydrophobic and have low water solubility, therefore posing issues in their absorption and bioavailability. Nonionic surfactants improve the solubility of hydrophobic drugs by entrapping them in their lipid bilayers. Two nonionic surfactants NODNH-16 and NODNH-18 are synthesized and characterized using different techniques i.e. EI-MS,

Indexed as

Amphotericin BLiposomesAnimalsHemolysisHydrazinesMiceSurface-Active AgentsAmphotericin BHydrazinesLiposomesSurface-Active AgentsbiocompatibilityCMCdrug deliveryself-assemblySynthesis

Identifiers

PMID36785530
PMCPMC9930833
OpenAlexW4320709583

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.