Evidence map›Paper›PMID 36788284›Full record

ArticleAmerican journal of reproductive immunology (New York, N.Y. : 1989)2023

Effects on neonatal immunoglobulin concentrations by infant mode of delivery in the upstate KIDS study (2008-2010).

Temilayo E Adeyeye, Laura E Jones, Edwina Yeung, Pauline Mendola, David A Lawrence, Shao Lin, Erin M Bell

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of reproductive immunology (New York, N.Y. : 1989), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Temilayo E AdeyeyeDepartment of Environmental Health Sciences, School of Public Health, State University of New York, Albany, New York, USA.
Laura E JonesDepartment of Epidemiology and Biostatistics, School of Public Health, State University of New York, Albany, New York, USA.
Edwina YeungDivision of Population Health Research, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, USA.
Pauline MendolaDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, State University of New York, Albany, New York, USA.
David A LawrenceDepartment of Environmental Health Sciences, School of Public Health, State University of New York, Albany, New York, USA.
Shao LinDepartment of Environmental Health Sciences, School of Public Health, State University of New York, Albany, New York, USA.
Erin M BellDepartment of Environmental Health Sciences, School of Public Health, State University of New York, Albany, New York, USA.
New York State Department of Health · USUniversity at Albany, State University of New York · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

NICHD NIH HHS HHSN267200700019CNICHD NIH HHS HHSN275201200005C
6 · The paper itself

Abstract

problemPrevious studies document an association between mode of delivery (MOD) and allergic conditions in children. Immunoglobulin (Ig) concentrations at birth may play a role. The goal of this study is to assess the impact of MOD on Ig concentrations at delivery from newborn dried blood spots (DBS). METHOD OF STUDY: The Upstate KIDS Study (2008-2010) is a prospective cohort of mother-child pairs recruited from New York State, excluding New York City. Ig subtypes IgA, IgE, IgG

resultsIgA, and the IgG subtypes IgG

conclusionsMOD may thus be related to neonatal immune profile. Results were found to be robust to sensitivity testing based on maternal complications and indication for CD. Clinical implications are unclear given the small levels of association found in newborns, but the result suggests greater susceptibility to infection, and further study is warranted.

Indexed as

Cesarean SectionParturitionFemaleHumansImmunoglobulin AImmunoglobulin GInfantInfant, NewbornPregnancyProspective StudiesImmunoglobulin AImmunoglobulin Gemergency cesarean deliveryimmunoglobulinsmode of deliverynewborn dried blood spotsplanned cesarean deliveryvaginal delivery

Identifiers

PMID36788284
PMCPMC11318237
OpenAlexW4320856132

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.