ArticleTheranostics2023
Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- Respiratory Models Reveal DNA Damage Response Modulation by Merkel Cell Polyomavirus.International journal of molecular sciences · 2026Article
- Transcriptional modulation of the PI3K/AKT/mTOR signaling pathway mediated by HPV16Exploration of targeted anti-tumor therapy · 2026Article
- HPV-driven breast carcinogenesis: associations with tumor severity, Ki67 expression and metastasis.Infectious agents and cancer · 2025Article
- De-escalation of radiotherapy in the treatment of human papillomavirus-associated oropharyngeal cancer.The Cochrane database of systematic reviews · 2025Article
- Tailoring an intravenously injectable oncolytic virus for augmenting radiotherapy.Cell reports. Medicine · 2025Article
- Viral oncogenesis in cancer: from mechanisms to therapeutics.Signal transduction and targeted therapy · 2025Review
- RANKL blockade inhibits cancer growth through reversing the tolerogenic profile of tumor-infiltrating (plasmacytoid) dendritic cells.Journal for immunotherapy of cancer · 2025Article
- Integrating bioinformatics to explore HPV-31 and HPV-52 E6/E7 proteins: from structural analysis to antigenic epitope prediction.Frontiers in immunology · 2025Article
- Prediction of Cervical Cancer Progression Leveraging HPV16 Integration-Related Genes.International journal of women's health · 2025Article
- Targeting synthetic lethality: an effective therapeutic approach in ovarian and endometrial cancers.Therapeutic advances in medical oncology · 2025Review
- Transcriptome-based model for predicting radiotherapy response in HNSCC patients.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025Article
- A Mitochondria-Related Signature in Diffuse Large B-Cell Lymphoma: Prognosis, Immune and Therapeutic Features.Cancer medicine · 2025Article
- Molecular aspects of cervical cancer: a pathogenesis update.Frontiers in oncology · 2024Review
- Virus-induced host genomic remodeling dysregulates gene expression, triggering tumorigenesis.Frontiers in cellular and infection microbiology · 2024Review
- Genome composition-based deep learning predicts oncogenic potential of HPVs.Frontiers in cellular and infection microbiology · 2024Article
- Oncoproteins E6 and E7 upregulate topoisomerase I to activate the cGAS-PD-L1 pathway in cervical cancer development.Frontiers in pharmacology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 4 institutions in 3 countries.
Diane BruyereLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Patrick RoncaratiLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Alizee LebeauLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Thomas LerhoLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Florian PoulainNamur Research Institute for Life Sciences (NARILIS), Integrated Veterinary Research Unit (URVI), University of Namur, Namur, Belgium.
Elodie HendrickLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Charlotte PilardLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Celia ReyndersLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Marie AncionLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Margaux LuyckxLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Michael RenardLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Yves JacobUnit of Molecular Genetics of RNA Viruses, UMR 3569, CNRS, Pasteur Institute, University of Paris Diderot, 75015 Paris, France.
Jean-Claude TwizereLaboratory of Signaling and Protein Interactions, GIGA-Molecular Biology of Diseases, University of Liege, 4000 Liege, Belgium.
Raphael PeifferMetastasis Research Laboratory, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Olivier PeulenMetastasis Research Laboratory, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Philippe DelvenneLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Pascale HubertLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
Alison McBrideLaboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA.
Nicolas GilletNamur Research Institute for Life Sciences (NARILIS), Integrated Veterinary Research Unit (URVI), University of Namur, Namur, Belgium.
Murielle MassonBiothechnology Superior School, UMR 7242, CNRS, University of Strasbourg, 67412 Illkirch, France.
Michael HerfsLaboratory of Experimental Pathology, GIGA-Cancer, University of Liege, 4000 Liege, Belgium.
University of Liège · BECentre National de la Recherche Scientifique · FRUniversity of Namur · BENational Institutes of Health · US
Funding
Replication mechanisms of human papillomaviruses (HPV)ZIAAI000713 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MCBRIDE, ALISON · 2009 to 2025
$12.4MAbstract
PubMed holds no abstract for this paper.
Indexed as
NeoplasmsOncogene Proteins, ViralPapillomavirus InfectionsCarrier ProteinsDNA DamageDNA RepairDNA Repair EnzymesHuman Papillomavirus VirusesHumansNuclear ProteinsPapillomavirus E7 ProteinsPhosphotransferases (Alcohol Group Acceptor)Carrier ProteinsDNA Repair EnzymesNuclear ProteinsOncogene Proteins, ViralPapillomavirus E7 ProteinsPhosphotransferases (Alcohol Group Acceptor)PNKP protein, humanPOLDIP2 protein, humanUVSSA protein, humanDNA damage and repairhuman papillomavirusprotein-protein interactome.radiotherapy
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.