Evidence map›Paper›PMID 36794404›Full record

ArticleDrug delivery2023

Brain-targeted delivery of Valsartan using solid lipid nanoparticles labeled with Rhodamine B; a promising technique for mitigating the negative effects of stroke.

Shereen A Sabry, Amal M Abd El Razek, Mohamed Nabil, Shaimaa M Khedr, Hanan M El-Nahas, Noura G Eissa

Open access · goldFull text read
In one paragraph

Article in Drug delivery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

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  13. Research progress in brain-targeted nasal drug delivery.Frontiers in aging neuroscience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shereen A SabryDepartment of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Amal M Abd El RazekDepartment of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Mohamed NabilPharmacology Department, Faculty of Pharmacy, New Valley University, Kharga, Egypt.
Shaimaa M KhedrPharmaceutical and Fermentation Industries Development Centre (PFIDC), City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab, Alexandria, Egypt.
Hanan M El-NahasDepartment of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.ORCID 0000-0002-9148-3276
Noura G EissaDepartment of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Zagazig University · EGCity of Scientific Research and Technological Applications · EGSouth Valley University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain is a vital organ that is protected from the general circulation and is distinguished by the presence of a relatively impermeable blood brain barrier (BBB). Blood brain barrier prevents the entry of foreign molecules. The current research aims to transport valsartan (Val) across BBB utilizing solid lipid nanoparticles (SLNs) approach to mitigate the adverse effects of stroke. Using a 3

Indexed as

NanoparticlesStrokeBrainDrug CarriersHumansLipidsLiposomesParticle SizeRhodaminesDrug CarriersLipid NanoparticlesLipidsLiposomesrhodamine BRhodaminesfactorial designphoton imagingsolid lipid nanoparticlesstroketransmission electron microscopyValsartan

Identifiers

PMID36794404
PMCPMC10003139
OpenAlexW4321004121

What Socratic holds

Textfull text, public
LicenceCC BY
measurements read64
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.