Evidence map›Paper›PMID 36794518›Full record

ReviewPerfusion2024

Adverse renal effects associated with cardiopulmonary bypass.

Benjamin Milne, Tom Gilbey, Filip De Somer, Gudrun Kunst

Open access · hybridAbstract readReview
In one paragraph

Review in Perfusion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. National Heart Center Perfusion Guidelines.Saudi medical journal · 2026
    Guideline
  3. Guideline
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Kidney Injury Following Cardiac Surgery: A Review of Our Current Understanding.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  12. Article
  13. Article
  14. Kidney PROTECTION after Cardiac Surgery with Intravenous Amino Acid Infusion.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Article
  15. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  16. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  17. Article
  18. Article
  19. Lactate and COFrontiers in cardiovascular medicine · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Benjamin MilneDepartment of Anaesthesia & Pain Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Tom GilbeyDepartment of Anaesthesia & Pain Medicine, King's College Hospital NHS Foundation Trust, London, UK.
Filip De SomerDepartment of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0001-7113-4565
Gudrun KunstDepartment of Anaesthesia & Pain Medicine, King's College Hospital NHS Foundation Trust, London, UK.ORCID 0000-0002-9789-1334
Ghent University Hospital · BEJohn Radcliffe Hospital · GBKing's College Hospital NHS Foundation Trust · GBKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac surgery on cardiopulmonary bypass (CPB) is associated with postoperative renal dysfunction, one of the most common complications of this surgical cohort. Acute kidney injury (AKI) is associated with increased short-term morbidity and mortality and has been the focus of much research. There is increasing recognition of the role of AKI as the key pathophysiological state leading to the disease entities acute and chronic kidney disease (AKD and CKD). In this narrative review, we will consider the epidemiology of renal dysfunction after cardiac surgery on CPB and the clinical manifestations across the spectrum of disease. We will discuss the transition between different states of injury and dysfunction, and, importantly, the relevance to clinicians. The specific facets of kidney injury on extracorporeal circulation will be described and the current evidence evaluated for the use of perfusion-based techniques to reduce the incidence and mitigate the complications of renal dysfunction after cardiac surgery.

Indexed as

Acute Kidney InjuryCardiac Surgical ProceduresCardiopulmonary BypassHumansKidneyPostoperative ComplicationsRetrospective StudiesRisk Factorsbypasscardiacinjurykidneysurgery

Identifiers

PMID36794518
PMCPMC10943608
OpenAlexW4321003194

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.