Evidence map›Paper›PMID 36797338›Full record

ReviewJournal of human hypertension2023

Mechanisms of sex and gender differences in hypertension.

Jane F Reckelhoff

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of human hypertension, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 52 citations in OpenAlex.

  1. Trial
  2. Influence ofAnnals of medicine · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Sexual dimorphism in benign adrenocortical tumours.European journal of endocrinology · 2025
    Review
  14. Article
  15. Urinary βJournal of xenobiotics · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jane F ReckelhoffDepartment of Cell and Molecular Biology, Women's Health Research Center, Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson, MS, USA. jreckelhoff@umc.edu.ORCID http://orcid.org/0000-0002-6606-4133
University of Mississippi Medical Center · US

Funding

STRUCTURAL VASCULAR ADAPTATION OF THE MICROCIRCULATIONP01HL051971 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI HALL, JOHN E · 1993 to 2018
$39.4M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Ashley C. Johnson, Babbette LaMarca · 2017 to 2026
$26.4M
Mechanisms of hypertension in women with polycystic ovary syndromeR01HL135089 · NHLBI · JOHN B. PIERCE LABORATORY, INC. · PI RECKELHOFF, JANE F, STACHENFELD, NINA · 2018 to 2021
$3.5M
Age-related Hypertension and Vascular Cognitive ImpairmentR01AG075963 · NIA · EMORY UNIVERSITY · PI David H Farb, Richard David Wainford · 2022 to 2026
$3.2M
NHLBI NIH HHS P01 HL051971NHLBI NIH HHS R01 HL135089NIA NIH HHS R01 AG075963NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

The mechanisms that control blood pressure are multifaceted including the sympathetic nervous system and the renin-angiotensin system leading to vasoconstriction and sodium reabsorption that causes a shift in the pressure-natriuesis relationship to higher blood pressures. Sex steroids can affect these mechanisms either directly or indirectly, and the effects may be different depending on the sex of the individual. This review will discuss some of the major blood pressure-controlling mechanisms and how sex steroids may affect them and the need for future studies to better clarify the mechanisms responsible for sex and gender differences in blood pressure control. New mechanisms that are identified, along with what is already known, will provide better tools for treatment of hypertension in men and women of all ethnicities and decrease the risk of cardiovascular disease in the future.

Indexed as

HypertensionBlood PressureFemaleHumansMaleRenin-Angiotensin SystemSex FactorsSteroidsSympathetic Nervous SystemSteroids

Identifiers

PMID36797338
OpenAlexW4321093046

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.