Evidence map›Paper›PMID 36803254›Full record

ReviewChannels (Austin, Tex.)2023

L-type calcium channels and neuropsychiatric diseases: Insights into genetic risk variant-associated genomic regulation and impact on brain development.

Madelyn R Baker, Andrew S Lee, Anjali M Rajadhyaksha

Open access · goldAbstract readReview
In one paragraph

Review in Channels (Austin, Tex.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Reinventing amlodipine.The Journal of pharmacology and experimental therapeutics · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Deletion ofFrontiers in cellular neuroscience · 2026
    Article
  9. Epigenetic Mechanisms of Suicidal Behavior Formation: A Review.Medical journal of the Islamic Republic of Iran · 2026
    Review
  10. Astrocytic abnormalities in brain-specificChannels (Austin, Tex.) · 2025
    Article
  11. Deletion ofbioRxiv : the preprint server for biology · 2025
    Article
  12. The Impact of Overexpression of the Mouse Ortholog ofBiological psychiatry global open science · 2025
    Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Madelyn R BakerNeuroscience Program, Weill Cornell Graduate School of Medical Sciences, New York, USA.
Andrew S LeeNeuroscience Program, Weill Cornell Graduate School of Medical Sciences, New York, USA.
Anjali M RajadhyakshaNeuroscience Program, Weill Cornell Graduate School of Medical Sciences, New York, USA.ORCID 0000-0002-8399-5466
Cornell University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
J. NRSA Training CoreTL1TR002386 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Genevieve Giny Fouda Amou ou · 2017 to 2026
$5.8M
Circuit and Synaptic Mechanisms of Endocannabinoid-Opioid CrosstalkR01DA054368 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Francis Sang Yong Lee, Anjali M Rajadhyaksha · 2022 to 2026
$3.5M
Molecular and circuit defects underlying different SCN2A mutations and ASDsR01MH118934 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI PITT, GEOFFREY S · 2019 to 2023
$3.2M
Investigating the mechanistic contribution of Cav1.2 channels in extinction of cocaine-associated memoriesR01DA053261 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI Anjali M Rajadhyaksha · 2022 to 2026
$2.6M
GABAergic Interneuron Dysfunction in Developing Cortical Circuits Underlying Autism Spectrum DisordersR01MH125006 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI DE MARCO GARCIA, NATALIA VANESA, RAJADHYAKSHA, ANJALI M · 2021 to 2025
$2.1M
The Role of Cav1.2 L-type Ca2+ Channels in Cocaine-Induced ReinstatementR01DA029122 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI RAJADHYAKSHA, ANJALI M · 2012 to 2016
$2.1M
L-Type Calcium Channel Mechanisms Mediating Comorbid Substance Use and Mood DisordersR01DA050454 · NIDA · YALE UNIVERSITY · PI ADDY, NII A · 2020 to 2024
$2.0M
NCATS NIH HHS TL1 TR002386NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NCI NIH HHS P30 CA008748NIDA NIH HHS R01 DA029122NIDA NIH HHS R01 DA050454NIDA NIH HHS R01 DA053261NIDA NIH HHS R01 DA054368NIMH NIH HHS R01 MH118934NIMH NIH HHS R01 MH125006
6 · The paper itself

Abstract

Recent human genetic studies have linked a variety of genetic variants in the

Indexed as

Calcium Channels, L-TypeGenome-Wide Association StudyAnimalsBrainGenomicsHumansNeuronsCalcium Channels, L-TypeCACNA1CCACNA1DCav1.2Cav1.3neuropsychiatric

Identifiers

PMID36803254
PMCPMC9980663
OpenAlexW4321352759

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.