ReviewBiomimetics (Basel, Switzerland)2023
Biomimetic Action of Zinc Hydroxyapatite on Remineralization of Enamel and Dentin: A Review.
Review in Biomimetics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 49 citations in OpenAlex.
- Evaluation of zinc oxide nanoparticle coated elastomeric modules and it's effect on Streptococcus mutans concentration and enamel mineralization - A randomized split mouth trial.Scientific reports · 2025Trial
- Clinical Status and Salivary aMMP-8 Evaluation of 0.12% Chlorhexidine Versus MicroRepairDentistry journal · 2026Article
- Materials and Techniques in Dentistry, Oral Surgery and Orthodontics (Second Edition).Materials (Basel, Switzerland) · 2026Article
- Effects of Different Zinc Modulations in Glass Ionomer Cements on Multi-Species Biofilm Formation and Human Tooth Demineralization: An In Vitro Study.Antibiotics (Basel, Switzerland) · 2026Article
- Health History, Health Condition, Health Behaviours and Health-Seeking Behaviours of Middle-Aged Women Living in a Modern Rural Community: A Survey Research.Nursing open · 2025Observational
- Time-Effect Comparative Evaluation of Three Remineralizing Agents on Artificial Enamel Lesions: A SEM-EDX In Vitro Study.Journal of clinical medicine · 2025Article
- Comparative Chemical and Physical Characterization of Biomimetic Versus Commercial Hydroxyapatites for Tooth Enamel Repair.Biomimetics (Basel, Switzerland) · 2025Article
- The effects and mechanisms underlying collagen-binding peptides MDPs on dentin remineralization: an in vitro study.BMC oral health · 2025Article
- Effect of Storage Temperature and Storage Time on the pH and Oxidation-Reduction Potential of Commercial Oral Moisturizers.Dentistry journal · 2025Article
- Green-Synthesized Nano-Silver Fluoride for Remineralization of Enamel Lesions in Primary Teeth: A Comparative In Vitro Study with SDF and SDF/KI.Dentistry journal · 2025Article
- Remineralizing Treatments for Dental Erosion and Sensitivity in Patients Suffering from Gastroesophageal Reflux Disease (GERD): Randomized Clinical Trial.Journal of clinical medicine · 2025Article
- Photocatalytic TiORSC advances · 2025Article
- Editorial for Oral Microbes and Human Health.Microorganisms · 2025Article
- An Ultrastructural, In-Situ Study on the Impact of Desensitizing Agents on Dentin.International dental journal · 2025Article
- Color Change and Color Stability of White Spot Lesions Treated with Resin Infiltration, Microabrasion, or Nano-Hydroxyapatite Remineralization: An In Vitro Study.Dentistry journal · 2025Article
- Clinical and Technological Evaluation of the Remineralising Effect of Biomimetic Hydroxyapatite in a Population Aged 6 to 18 Years: A Randomized Clinical Trial.Bioengineering (Basel, Switzerland) · 2025Article
- Occlusion of Dentinal Tubules by Nanohydroxyapatite and Zinc Carbonate Hydroxyapatite-Based Toothpastes as Desensitizing Agents: An in Vitro Study.Frontiers in dentistry · 2025Article
- Dentin Hypersensitivity Treated With Diode Laser and Aminefluoride: A Randomized Clinical Trial.International journal of dentistry · 2025Article
- Effect of Zinc on improving silver diamine fluoride-derived tooth discoloration in vitro.BMC oral health · 2024Article
- Effect of Zinc on Improving Silver Diamine Fluoride-derived Tooth Discoloration in Vitro.Research square · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomimetic zinc-carbonate hydroxyapatite technology was developed to realize materials that mimic the natural hydroxyapatite of enamel and dentin and possess good activity in terms of affinity to adhere to these biological tissues. The chemical and physical characteristics of this active ingredient allows the hydroxyapatite itself to be particularly similar to dental hydroxyapatite, enhancing the bond between biomimetic hydroxyapatite and dental hydroxyapatite. The aim of this review is to assess the efficacy of this technology in terms of benefits for enamel and dentin and reduction of dental hypersensitivity. MATERIALS AND
methodsA literature search (Pubmed/MEDLINE and Scopus) of articles from 2003 to 2023 was conducted to analyze studies focused on the use of zinc-hydroxyapatite products. Duplicates were eliminated from the 5065 articles found, leaving 2076 articles. Of these, 30 articles were analyzed based on the use of products with zinc-carbonate hydroxyapatite in these studies.
results30 articles were included. Most of the studies showed benefits in terms of remineralization and prevention of enamel demineralization in terms of occlusion of the dentinal tubules and reduction of dentinal hypersensitivity.
conclusionOral care products such as toothpaste and mouthwash with biomimetic zinc-carbonate hydroxyapatite were shown to provide benefits according to the aims of this review.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.