Evidence map›Paper›PMID 36810432›Full record

ArticleJournal of xenobiotics2023

Phytotherapy and Drugs: Can Their Interactions Increase Side Effects in Cancer Patients?

Sarah Allegra, Silvia De Francia, Francesca Turco, Ilenia Bertaggia, Francesco Chiara, Tiziana Armando, Silvana Storto, Maria Valentina Mussa

Open access · goldAbstract read
In one paragraph

Article in Journal of xenobiotics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. A Systematic Review of Cardio-Metabolic Properties ofAntioxidants (Basel, Switzerland) · 2024
    Review
  3. Beneficial Effects ofPlants (Basel, Switzerland) · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sarah AllegraDepartment of Clinical and Biological Sciences, Clinical Pharmacology Service Franco Ghezzo, University of Turin, San Luigi Gonzaga University Hospital, Regione Gonzole 10, 10043 Orbassano, Italy.ORCID 0000-0003-4933-0011
Silvia De FranciaDepartment of Clinical and Biological Sciences, Clinical Pharmacology Service Franco Ghezzo, University of Turin, San Luigi Gonzaga University Hospital, Regione Gonzole 10, 10043 Orbassano, Italy.
Francesca TurcoDepartment of Public Health, University of Turin, Città della Salute e della Scienza University Hospital, 10124 Turin, Italy.
Ilenia BertaggiaDepartment of Public Health, University of Turin, Città della Salute e della Scienza University Hospital, 10124 Turin, Italy.
Francesco ChiaraDepartment of Clinical and Biological Sciences, Clinical Pharmacology Service Franco Ghezzo, University of Turin, San Luigi Gonzaga University Hospital, Regione Gonzole 10, 10043 Orbassano, Italy.
Tiziana ArmandoDepartment of Public Health, University of Turin, Città della Salute e della Scienza University Hospital, 10124 Turin, Italy.
Silvana StortoDepartment of Public Health, University of Turin, Città della Salute e della Scienza University Hospital, 10124 Turin, Italy.
Maria Valentina MussaDepartment of Public Health, University of Turin, Città della Salute e della Scienza University Hospital, 10124 Turin, Italy.ORCID 0000-0001-9099-4712
University of Turin · ITOspedale San Luigi Gonzaga · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe use of herbs to treat illnesses was common in all historical eras. Our aim was to describe the phytotherapeutic substances that cancer patients use most commonly, and to determine whether their use can increase side effects.

methodsThis was a retrospective and descriptive study conducted among older adults actively undergoing chemotherapy, admitted at the Oncology DH Unit (COES) of the Molinette Hospital AOU Città della Salute e della Scienza in Turin (Italy). Data collection was conducted through the distribution of self-compiled and closed-ended questionnaires during chemotherapy treatment.

resultsA total of 281 patients were enrolled. Evaluating retching and sage consumption was statistically significant in multivariate analysis. The only risk factor for dysgeusia was chamomile consumption. Ginger, pomegranate, and vinegar use were retained as mucositis predictors.

conclusionsPhytotherapeutic use needs more attention in order to decrease the risks of side effects, toxicity, and ineffective treatment. The conscious administration of these substances should be promoted for safe use and to provide the reported benefits.

Indexed as

chemotherapyphytotherapytoxicity

Identifiers

PMID36810432
PMCPMC9945131
OpenAlexW4318776473

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.