ReviewNeurology international2023
Monocyte to HDL and Neutrophil to HDL Ratios as Potential Ischemic Stroke Prognostic Biomarkers.
Review in Neurology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neutrophil to high-density lipoprotein cholesterol ratio and prognosis in acute ischemic stroke: a systematic review and meta-analysis.BMC neurology · 2026Pooled it
- The monocyte-to-HDL cholesterol ratio (MHR) modifies the association between dietary patterns and depression: a sex-specific analysis.European archives of psychiatry and clinical neuroscience · 2026Article
- Association of composite biomarkers with imaging burden in cerebral small vessel disease.Lipids in health and disease · 2026Article
- Study on the predictive value of NHR and UHR levels in early pregnancy for gestational diabetes mellitus: based on a retrospective analysis.Frontiers in endocrinology · 2026Article
- Investigation of Peripheral Inflammatory Biomarkers in Trichotillomania.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2026Article
- Association of Inflammation-Based Ratios with Endothelial Dysfunction Markers and Clinical Parameters in Limited Cutaneous Systemic Sclerosis.Journal of clinical medicine · 2025Article
- Systemic Inflammation and Oxidative Stress Markers in Patients With Medication Overuse Headache.Brain and behavior · 2025Article
- The Association of Systemic Inflammatory Response Index and Neutrophil-to-High-Density Lipoprotein Ratio Mediated by Fasting Blood Glucose with 90-Day Prognosis in Acute Ischemic Stroke Patients.Neuroepidemiology · 2025Observational
- Neutrophil extracellular traps in ischemic stroke: mechanisms, clinical implications, and therapeutic potential.Frontiers in neurology · 2025Review
- Elevated monocyte-to-high-density lipoprotein ratio is associated with increased risk of cognitive impairment and severe cerebral small vessel disease burden.Frontiers in aging neuroscience · 2025Article
- Predictive Utility of PLR and Platelet-to-LDL Ratio for in-Stent Restenosis Following Carotid Artery Stenting.Vascular health and risk management · 2025Article
- Associations of novel blood-derived markers of inflammation with blood pressure, arterial stiffness and heart rate in young adults.Frontiers in cardiovascular medicine · 2025Article
- Predictive nomogram for ischemic stroke risk in clear cell renal cell carcinoma patients.Scientific reports · 2024Article
- Article
- The Aggregate Index of Systemic Inflammation as a Predictor of Mortality in Stroke Patients.Cureus · 2024Article
- Clinical and Diagnostic Value of High-Density Lipoprotein-Based Inflammatory Indices and Lipid Ratios in Young Adults with Schizophrenia.Journal of inflammation research · 2024Article
- Using a k-means clustering to identify novel phenotypes of acute ischemic stroke and development of its Clinlabomics models.Frontiers in neurology · 2024Article
- A cross-sectional study of factors associated with carotid atherosclerosis.Frontiers in physiology · 2024Article
- From Admission to Discharge: Predicting National Institutes of Health Stroke Scale Progression in Stroke Patients Using Biomarkers and Explainable Machine Learning.Journal of personalized medicine · 2023Article
- Investigating the Predictive Value of Thyroid Hormone Levels for Stroke Prognosis.Neurology international · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Ischemic stroke (IS) exhibits significant heterogeneity in terms of etiology and pathophysiology. Several recent studies highlight the significance of inflammation in the onset and progression of IS. White blood cell subtypes, such as neutrophils and monocytes, participate in the inflammatory response in various ways. On the other hand, high-density lipoproteins (HDL) exhibit substantial anti-inflammatory and antioxidant actions. Consequently, novel inflammatory blood biomarkers have emerged, such as neutrophil to HDL ratio (NHR) and monocyte to HDL ratio (MHR). Literature research of two databases (MEDLINE and Scopus) was conducted to identify all relevant studies published between 1 January 2012 and 30 November 2022 dealing with NHR and MHR as biomarkers for IS prognosis. Only full-text articles published in the English language were included. Thirteen articles have been traced and are included in the present review. Our findings highlight the utility of NHR and MHR as novel stroke prognostic biomarkers, the widespread application, and the calculation of which, along with their inexpensive cost, make their clinical application extremely promising.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.