ArticleNature communications2023
Prolonged experimental CD4
Open access · goldAbstract read
In one paragraph
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 12 citations in OpenAlex.
- Impact of a factor Xa inhibitor (apixaban) on SIV pathogenesis and response to antiretroviral therapy.JCI insight · 2026Article
- Immune Dysregulation in HIV-TB Co-Infection: Role of Cytokines and T Cell Biomarkers-A Narrative Review.Pathogens (Basel, Switzerland) · 2026Review
- It's all in the gut: the central role of the gut and microbiome in preventing disease progression in simian immunodeficiency viruses infected African nonhuman primates.Current opinion in HIV and AIDS · 2025Review
- Viremic non-progression in HIV/SIV infection: A tied game between virus and host.Cell reports. Medicine · 2025Review
- The heart of the matter: modeling HIV-associated cardiovascular comorbidities in nonhuman primate models.Frontiers in cellular and infection microbiology · 2025Review
- Plasma lipidomic alterations during pathogenic SIV infection with and without antiretroviral therapy.Frontiers in immunology · 2025Article
- Rapid systemic spread and minimal immune responses following SIVsab intrarectal transmission in African green monkeys.JCI insight · 2024Article
- Article
- Review
- The Intersection of HIV and Pulmonary Vascular Health: From HIV Evolution to Vascular Cell Types to Disease Mechanisms.Journal of vascular diseases · 2024Article
- CAR T cells for treating autoimmune diseases.RMD open · 2023Review
- The Role of Gut Dysbiosis in the Loss of Intestinal Immune Cell Functions and Viral Pathogenesis.Microorganisms · 2023Review
- Walk on the wild side: SIV infection in African non-human primate hosts-from the field to the laboratory.Frontiers in immunology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 1 country.
Quentin Le HingratDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-9017-4941
Paola SetteDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Cuiling XuDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Andrew R RahmbergBarrier Immunity Section, Lab of Viral Diseases, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.ORCID 0000-0002-6306-4584
Lilas TarnusDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Haritha AnnapureddyDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Adam KleinmanDivision of Infectious Diseases, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Egidio Brocca-CofanoDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Ranjit SivanandhamDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-7431-8415
Sindhuja SivanandhamDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0001-6328-3288
Tianyu HeDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Daniel J CapreriDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Dongzhu MaDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Jacob D EstesVaccine and Gene Therapy Institute, Oregon Health & Science University, Portland, OR, USA.
Jason M BrenchleyBarrier Immunity Section, Lab of Viral Diseases, Division of Intramural Research, NIAID, NIH, Bethesda, MD, USA.
Cristian ApetreiDivision of Infectious Diseases, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-0322-7185
Ivona PandreaDepartment of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. pandrea@pitt.edu.ORCID 0000-0002-4041-2961
University of Pittsburgh · USNational Institute of Allergy and Infectious Diseases · USOregon National Primate Research Center · US
Funding
SIV Pathogenesis in African Green Monkeys and Pigtailed MacaquesR01HL117715 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VASILE PANDREA, IVONA · 2012 to 2021
$7.0MInterventions to Reduce Hypercoagulability in Old SIV-Infected NHPsR01HL123096 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VASILE PANDREA, IVONA · 2015 to 2025
$6.8MResource CoreP40OD028116 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Diogo Magnani · 2020 to 2026
$5.9MAssessing the Role of GI Tract Dysfunction to HIV/SIV Disease ProgressionR01DK113919 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CRISTIAN APETREI, Ivona Vasile-Pandrea · 2017 to 2026
$5.7MNew Strategy to Improve Gastrointestinal Health in SIV/HIVR01DK119936 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI APETREI, CRISTIAN · 2018 to 2022
$5.1MImpact of metabolic programing of T cells from the GI tract and related tissues on HIV reservoir seeding, maintenance and reactivationR01DK131476 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CRISTIAN APETREI · 2021 to 2026
$3.9MAnimal Model for Testing SIV Latency Reversal StrategiesR01AI119346 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI APETREI, CRISTIAN · 2015 to 2019
$3.4MMyocardial Vulnerability to Ischemia-Induced Dysfunction and Heart Failure: The Impact of HIV/SIV, ART, and Targeted ImmunotherapyR01HL154862 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI FEINSTEIN, MATTHEW JOEL, VASILE PANDREA, IVONA · 2020 to 2023
$3.1MMechanistic Studies of Gut Dysfunction Exacerbation due to SARS-CoV-2 in HIV/SIV infected IndividualsR01DK130481 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VASILE PANDREA, IVONA · 2021 to 2023
$1.2MNHLBI NIH HHS R01 HL117715NHLBI NIH HHS R01 HL123096NHLBI NIH HHS R01 HL154862NIAID NIH HHS R01 AI119346NIDDK NIH HHS R01 DK113919NIDDK NIH HHS R01 DK119936NIDDK NIH HHS R01 DK130481NIDDK NIH HHS R01 DK131476NIH HHS P40 OD028116
Abstract
CD4
Indexed as
Acquired Immunodeficiency SyndromeHIV InfectionsSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAnimalsCD4-Positive T-LymphocytesChlorocebus aethiopsDisease Progression
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.