Evidence map›Paper›PMID 36813993›Full record

ArticleLeukemia2023

Patients with Down syndrome can be included in early phase clinical trials- a report from the T2016-003 Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) study.

N Gossai, D Bhojwani, E S Schafer, B H Chang, L Pommert, A Verma, J Malvar, Y Y Chi, J Hitzler, M J Burke and 1 more

Abstract readLetter
PubMed Publisher
In one paragraph

Article in Leukemia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

N GossaiCenter for Cancer and Blood Disorders, Children's Minnesota, Minneapolis, MN, USA. nathan.gossai@childrensmn.org.ORCID 0000-0003-1693-4898
D BhojwaniCancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-7559-7927
E S SchaferTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
B H ChangDepartment of Pediatrics, Oregon Health and Science University, Portland, OR, USA.ORCID 0000-0003-3783-1820
L PommertDivision of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.ORCID 0000-0001-8760-5202
A VermaPediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0001-6555-7924
J MalvarCancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Y Y ChiCancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA, USA.
J HitzlerDivision of Hematology Oncology, The Hospital for Sick Children, Toronto, ON, Canada.ORCID 0000-0003-1158-186X
M J BurkeDivision of Pediatric Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0001-6626-2773
K R RabinTexas Children's Cancer Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.

Funding

RESEARCH TRAINING IN TRANSFUSION SCIENCET32HL007209 · NHLBI · VERSITI WISCONSIN, INC. · PI WHITE, II, GILBERT C. · 1985 to 2019
$2.9M
NHLBI NIH HHS T32 HL007209
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Down SyndromeLeukemiaLymphomaHumans

Identifiers

PMID36813993

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.