Evidence map›Paper›PMID 36815840›Full record

ArticleAntimicrobial agents and chemotherapy2023

Organoselenium Has a Potent Fungicidal Effect on Cryptococcus neoformans and Inhibits the Virulence Factors.

Daniel Felipe Freitas De Jesus, Aline Luiza Duarte De Freitas, Isadora Maria De Oliveira, Larissa Costa De Almeida, Rafael Wesley Bastos, Cristina de Castro Spadari, Analy Sales de Azevedo Melo, Daniel de Assis Santos, Letícia Veras Costa-Lotufo, Flavia C G Reis and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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  6. Pathogens (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Daniel Felipe Freitas De JesusInstitute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Aline Luiza Duarte De FreitasInstitute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Isadora Maria De OliveiraSchool of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Larissa Costa De AlmeidaInstitute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Rafael Wesley BastosCenter of Biosciences, Federal University of Rio Grande do Norte (UFRN), Natal, Brazil.
Cristina de Castro SpadariInstitute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Analy Sales de Azevedo MeloDepartment of Medicine, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
Daniel de Assis SantosInstitute of Biomedical Sciences, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil.
Letícia Veras Costa-LotufoInstitute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.ORCID 0000-0003-1861-5153
Flavia C G ReisCarlos Chagas Institute, Oswaldo Cruz Foundation, Curitiba, Brazil.
Marcio L RodriguesCarlos Chagas Institute, Oswaldo Cruz Foundation, Curitiba, Brazil.
Hélio Alexandre StefaniSchool of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil.
Kelly IshidaInstitute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.ORCID 0000-0002-4602-0926
Universidade de São Paulo · BRFundação Carlos Chagas · BRUniversidade Federal de Minas Gerais · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcosis therapy is often limited by toxicity problems, antifungal tolerance, and high costs. Studies approaching chalcogen compounds, especially those containing selenium, have shown promising antifungal activity against pathogenic species. This work aimed to evaluate the

Indexed as

Antifungal AgentsCryptococcus neoformansAnimalsLarvaMothsVirulence FactorsAntifungal AgentsVirulence FactorsantifungalcapsuleCryptococcusGalleria mellonellaquinolineseleniumtitan cellvirulence

Identifiers

PMID36815840
PMCPMC10019174
OpenAlexW4321610955

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.