Evidence map›Paper›PMID 36817442›Full record

ReviewFrontiers in immunology2023

Inflammatory response: The target for treating hyperpigmentation during the repair of a burn wound.

Chi Zhong, Geao Liang, Peiting Li, Ke Shi, Fuyin Li, Jianda Zhou, Dan Xu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
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  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Chi ZhongDepartment of Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Geao LiangDepartment of Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Peiting LiDepartment of Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Ke ShiDepartment of Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Fuyin LiDepartment of Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Jianda ZhouDepartment of Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Dan XuDepartment of Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China.
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperpigmentation is a common complication in patients with burn injuries during wound healing; however, the mechanisms underlying its occurrence and development remain unclear. Recently, postinflammatory hyperpigmentation (PIH) was found to result from overproduction of melanin. Local or systemic inflammatory responses are often observed in patients who develop hyperpigmentation. However, we lack studies on the relationship between PIH and burn injury. Therefore, we comprehensively reviewed the existing literature on the melanogenesis of the skin, inflammatory mechanisms in pigmentation, and local or systemic alteration in inflammatory cytokines in patients suffering from burn trauma to elucidate the relationship between PIH and burn injury. We believe that this review will guide further research on regulating melanin production in the burn management process.

Indexed as

HyperpigmentationMelaninsHumansMelaninsburn woundcytokineshyperpigmentationinflammatory responsepostinflammatory hyperpigmentationtreatment

Identifiers

PMID36817442
PMCPMC9929571
OpenAlexW4318817333

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.