Evidence map›Paper›PMID 36819031›Full record

ReviewFrontiers in microbiology2023

Advances in the preclinical characterization of the antimicrobial peptide AS-48.

Rubén Cebrián, Marta Martínez-García, Matilde Fernández, Federico García, Manuel Martínez-Bueno, Eva Valdivia, Oscar P Kuipers, Manuel Montalbán-López, Mercedes Maqueda

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Applied and environmental microbiology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Rubén CebriánDepartment of Clinical Microbiology, Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital San Cecilio, Granada, Spain.
Marta Martínez-GarcíaDepartment of Molecular Genetics, University of Groningen, Groningen, Netherlands.
Matilde FernándezDepartment of Microbiology, University of Granada, Granada, Spain.
Federico GarcíaDepartment of Clinical Microbiology, Instituto de Investigación Biosanitaria Ibs.GRANADA, University Hospital San Cecilio, Granada, Spain.
Manuel Martínez-BuenoDepartment of Microbiology, University of Granada, Granada, Spain.
Eva ValdiviaDepartment of Microbiology, University of Granada, Granada, Spain.
Oscar P KuipersDepartment of Molecular Genetics, University of Groningen, Groningen, Netherlands.
Manuel Montalbán-LópezDepartment of Microbiology, University of Granada, Granada, Spain.
Mercedes MaquedaDepartment of Microbiology, University of Granada, Granada, Spain.
Universidad de Granada · ESInstituto de Investigación Biosanitaria de Granada · ESUniversity of Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is a natural and inevitable phenomenon that constitutes a severe threat to global public health and economy. Innovative products, active against new targets and with no cross- or co-resistance with existing antibiotic classes, novel mechanisms of action, or multiple therapeutic targets are urgently required. For these reasons, antimicrobial peptides such as bacteriocins constitute a promising class of new antimicrobial drugs under investigation for clinical development. Here, we review the potential therapeutic use of AS-48, a head-to-tail cyclized cationic bacteriocin produced by

Indexed as

antimicrobial peptideantimicrobial resistanceAS-48bacteriocinenterocin

Identifiers

PMID36819031
PMCPMC9936517
OpenAlexW4318999635

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.