Evidence map›Paper›PMID 36821646›Full record

ArticleAge and ageing2023

Comparison of sex differences in cognitive function in older adults between high- and middle-income countries and the role of education: a population-based multicohort study.

Mikaela Bloomberg, Aline Dugravot, Andrew Sommerlad, Mika Kivimäki, Archana Singh-Manoux, Séverine Sabia

Open access · hybridAbstract read
In one paragraph

Article in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
15.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Cross-Sectional Associations of Body Mass Index With Disability Across High- and Middle-Income Countries in 2002-2006 and 2015-2018.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mikaela BloombergDepartment of Epidemiology and Public Health, University College London, UK.ORCID 0000-0003-2453-6283
Aline DugravotUniversité Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative diseases, France.
Andrew SommerladDivision of Psychiatry, University College London, UK.
Mika KivimäkiDepartment of Epidemiology and Public Health, University College London, UK.
Archana Singh-ManouxDepartment of Epidemiology and Public Health, University College London, UK.ORCID 0000-0002-1244-5037
Séverine SabiaDepartment of Epidemiology and Public Health, University College London, UK.
Inserm · FRUniversity College London · GB

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
China Health and Retirement Longitudinal StudyR01AG037031 · NIA · PEKING UNIVERSITY · PI STRAUSS, JOHN A, WANG, YAFENG · 2010 to 2024
$15.1M
Education, socioeconomic status and Aging: transitions from multimorbidity to functional limitations and mortalityR01AG056477 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2018 to 2022
$2.8M
Role of mid- and late-life risk factors in social inequalities in Alzheimer's Disease and Related DementiasRF1AG062553 · NIA · INSERM PARIS 5 · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2019 to 2019
$1.5M
China Health and Retirement Longitudinal Study - PilotR21AG031372 · NIA · PEKING UNIVERSITY · PI ZHAO, YAOHUI · 2007 to 2008
$273k
Medical Research Council MR/S011676/1NIA NIH HHS R01 AG018016NIA NIH HHS R01 AG037031NIA NIH HHS R01 AG056477NIA NIH HHS R21 AG031372NIA NIH HHS RF1 AG062553NIA NIH HHS U01 AG009740Wellcome Trust
6 · The paper itself

Abstract

backgroundThe extent to which education explains variations in sex differences in cognitive function between countries at different levels of economic development is unknown. We examined the role of education in sex differences in four cognitive domains in high- and middle-income countries.

methodsAnalyses were based on 70,846 participants, aged 60 years and older, in cohort studies from a high-income (United States) and four middle-income countries (Mexico, Brazil, China, and India). We used weighted linear models to allow nationally-representative comparisons of sex differences in orientation, memory, attention, and fluency using the United States as the reference, before and after adjustment for education, and after stratification by education.

resultsFemales had lower levels of education than males in all countries, particularly in India. Before adjustment for education, sex differences in orientation and attention in all middle-income countries, memory in Brazil, China, and India, and fluency in India were less favourable to females than in the United States (P < 0.010). For example, females outperformed males in memory in the United States (mean difference [male-female scores] = -0.26 standard deviations [95% CI -0.30, -0.22]) but not in China (0.15 [0.09, 0.21]) or India (0.16 [0.13, 0.19]). Adjustment for education attenuated these sex differences. In analyses stratified by education, there were minimal sex differences in the high education group in all countries.

conclusionEducation contributes to larger female disadvantages in cognitive function at older ages in middle-income countries compared with the United States. Gender equity in education is an important target to reduce sex disparities in cognitive function globally.

Indexed as

Developing CountriesSex CharacteristicsAgedCognitionEducational StatusFemaleHumansIncomeMaleMiddle AgedUnited Statescognitioncognitive agingcognitive functioncomparative studyhealth inequalitiesolder people

Identifiers

PMID36821646
PMCPMC9949595
OpenAlexW4321610327

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.