Evidence map›Paper›PMID 36822397›Full record

ArticleThe Journal of nutrition2023

Positive Health Outcomes Associated with Live Microbe Intake from Foods, Including Fermented Foods, Assessed using the NHANES Database.

Colin Hill, Daniel J Tancredi, Christopher J Cifelli, Joanne L Slavin, Jaime Gahche, Maria L Marco, Robert Hutkins, Victor L Fulgoni, Daniel Merenstein, Mary Ellen Sanders

Abstract read
In one paragraph

Article in The Journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  9. Association between dietary active microbe intake and dental caries among American adults : Evidence from the NHANES database.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Colin HillAPC Microbiome Ireland, University College Cork, Cork, Ireland.
Daniel J TancrediDepartment of Pediatrics, UC Davis School of Medicine, Sacramento, CA, United States.
Christopher J CifelliNational Dairy Council, Rosemont, IL, United States.
Joanne L SlavinDepartment of Food Science and Nutrition, University of Minnesota, Minneapolis, MN, United States.
Jaime GahcheOffice of Dietary Supplements, NIH, Bethesda, MD, United States.
Maria L MarcoDepartment of Food Science and Technology, University of California-Davis, Davis, CA, United States.
Robert HutkinsDepartment of Food Science and Technology, University of Nebraska, Lincoln, NE, United States.
Victor L FulgoniNutrition Impact, LLC, Battle Creek, MI, United States.
Daniel MerensteinResearch Programs Family Medicine, Georgetown University Medical Center, Department of Human Science, School of Health, Georgetown University, Washington, DC, United States.
Mary Ellen SandersInternational Scientific Association for Probiotics and Prebiotics, Centennial, CO, United States. Electronic address: maryellen@isappscience.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLive dietary microbes have been hypothesized to contribute to human health but direct evidence is lacking.

objectivesThis study aimed to determine whether the dietary consumption of live microbes is linked to improved health outcomes.

methodsData from the NHANES 2001-2018 were used to assess microbial intake and their adjusted associations with selected physiological parameters (e.g., blood pressure, anthropometric measures, and biomarkers) among adults aged 19 y and older. Regression models were constructed to assess the microbial intake with each physiological parameter and adjusted for demographics and other covariates. Microbial intake was assessed as both a continuous variable and a 3-level categorical variable. Fermented foods were assessed in a separate model.

resultsIn continuous models, an additional 100-g intake of microbe-containing foods was associated with a lower systolic blood pressure (regression coefficient: -0.331; 95% CI: -0.447, -0.215 mm Hg), C-reactive protein (-0.013; 95% CI: -0.019, -0.008 mg/dL), plasma glucose -0.347; 95% CI: -0.570, -0.124 mg/dL), plasma insulin (-0.201; 95% CI: -0.304, -0.099 μU/mL), triglyceride (-1.389; 95% CI: -2.672, -0.106 mg/dL), waist circumference (-0.554; 95% CI: -0.679, -0.428 cm), and BMI -0.217; 95% CI: -0.273, -0.160 kg/m

conclusionsTo our knowledge, this study is the first to quantify, in a nationally representative data set of American adults and using stable sets of covariates in the regression models, the adjusted associations of dietary intakes of live microbes with a variety of outcomes, such as anthropometric measures, biomarkers, and blood pressure levels. Our findings suggest that foods with higher microbial concentrations are associated with modest health improvements across a range of outcomes.

Indexed as

Fermented FoodsAdultBiomarkersBody Mass IndexHumansNutrition SurveysOutcome Assessment, Health CareUnited StatesBiomarkersfermented foodhealth promotion/disease preventionInternational Scientific Association for Probiotics and PrebioticsISAPPlive dietary microbesNHANESprobiotics

Identifiers

PMID36822397
PMCPMC10196563

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.