Evidence map›Paper›PMID 36825370›Full record

ReviewImmunology and cell biology2023

T follicular helper cell responses to SARS-CoV-2 vaccination among healthy and immunocompromised adults.

Mollie Ailie Acheson Boyd, Alexandra Carey Hoppe, Anthony D Kelleher, C Mee Ling Munier

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Immunology and cell biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mollie Ailie Acheson BoydImmunovirology and Pathogenesis Program, The Kirby Institute, UNSW, Sydney, NSW, 2052, Australia.ORCID 0000-0002-4980-7193
Alexandra Carey HoppeImmunovirology and Pathogenesis Program, The Kirby Institute, UNSW, Sydney, NSW, 2052, Australia.
Anthony D KelleherImmunovirology and Pathogenesis Program, The Kirby Institute, UNSW, Sydney, NSW, 2052, Australia.
C Mee Ling MunierImmunovirology and Pathogenesis Program, The Kirby Institute, UNSW, Sydney, NSW, 2052, Australia.
UNSW Sydney · AU

Funding

National Health and Medical Research Council 1149990National Health and Medical Research Council 2012863St. Vincent's Clinic Foundation 2021University of New South Wales RTP
6 · The paper itself

Abstract

The worldwide rollout of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccinations in the last 2 years has produced a multitude of studies investigating T-cell responses in the peripheral blood and a limited number in secondary lymphoid tissues. As a key component to an effective immune response, vaccine-specific T follicular helper (Tfh) cells are localized in the draining lymph node (LN) and assist in the selection of highly specific B-cell clones for the production of neutralizing antibodies. While these cells have been noted in the blood as circulating Tfh (cTfh) cells, they are not often taken into consideration when examining effective CD4

Indexed as

COVID-19T-Lymphocytes, Helper-InducerAdultCOVID-19 VaccinesHumansSARS-CoV-2T Follicular Helper CellsVaccinationCOVID-19 VaccinesCD4 T cellscirculating T follicular helper cells (cTfh)fine needle aspiration (FNA)fine-needle biopsy (FNB)Lymph nodeSARS-CoV-2 vaccinationT follicular helper cells (Tfh)

Identifiers

PMID36825370
PMCPMC10952589
OpenAlexW4321748569

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.