Evidence map›Paper›PMID 36825592›Full record

ArticleInternational journal of oncology2023

Dual targets of lethal apoptosis and protective autophagy in liver cancer with periplocymarin elicit a limited therapeutic effect.

Yuanyuan Hao, Tao Song, Mingye Wang, Tongtong Li, Chi Zhao, Ting Li, Yunlong Hou, Hongjiang He

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Chinese herbal medicines · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yuanyuan HaoCollege of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, P.R. China.
Tao SongCollege of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, P.R. China.
Mingye WangCollege of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, P.R. China.
Tongtong LiCollege of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, P.R. China.
Chi ZhaoHebei Medical University, Shijiazhuang, Hebei 050017, P.R. China.
Ting LiDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang 150081, P.R. China.
Yunlong HouCollege of Integrated Traditional Chinese and Western Medicine, Hebei University of Chinese Medicine, Shijiazhuang, Hebei 050200, P.R. China.
Hongjiang HeDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang 150081, P.R. China.
Hebei University of Chinese Medicine · CNHarbin Medical University · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac glycosides (CGs) are candidate anticancer agents that function by increasing [Ca

Indexed as

Cardiac GlycosidesLiver NeoplasmsAMP-Activated Protein KinasesAnimalsApoptosisAutophagyCell Line, TumorCell ProliferationHumansMiceMice, NudeAMP-Activated Protein KinasesCardiac Glycosidesperiplocymarinapoptosisautophagycardiac glycosidesliver cancerperiplocymarin

Identifiers

PMID36825592
PMCPMC9946806
OpenAlexW4321456854

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.