Evidence map›Paper›PMID 36826003›Full record

ArticleCurrent issues in molecular biology2023

Evaluation of Antidiabetic, Antioxidant and Anti-Hyperlipidemic Effects of

Manoj M Gadewar, Prashanth G K, Prabhu Chandra Mishra, Ghulam Md Ashraf, Majed N Almashjary, Steve Harakeh, Vijay Upadhye, Abhijit Dey, Pallavi Singh, Niraj Kumar Jha and 1 more

Open access · goldAbstract read
In one paragraph

Article in Current issues in molecular biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 3 countries.

Manoj M GadewarDepartment of Pharmacology, School of Medical and Allied Sciences, K.R. Mangalam University, Gurgaon 122103, India.ORCID 0000-0002-0787-6916
Prashanth G KDepartment of Chemistry, Sir M. Visvesvaraya Institute of Technology, Visvesvaraya Technological University, Bengaluru 562157, India.ORCID 0000-0001-6691-4030
Prabhu Chandra MishraDepartment of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida 201310, India.
Ghulam Md AshrafDepartment of Medical Laboratory Sciences, College of Health Sciences, and Sharjah Institute for Medical Research, University of Sharjah, Sharjah 27272, United Arab Emirates.ORCID 0000-0002-9820-2078
Majed N AlmashjaryDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-6619-0287
Steve HarakehKing Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Vijay UpadhyeCentre of Research for Development (CR4D), Parul University (DSIR-SIRO Recognized) PO Limda, Tal Waghodiya, Vadodara 391760, India.ORCID 0000-0002-8821-1720
Abhijit DeyDepartment of Life Sciences, Presidency University, 86/1 College Street, Kolkata 700032, India.ORCID 0000-0002-5750-0802
Pallavi SinghDepartment of Biotechnology, Graphic Era Deemed to be University, Dehradun 248002, India.ORCID 0000-0003-4537-4607
Niraj Kumar JhaDepartment of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida 201310, India.ORCID 0000-0001-9486-4069
Saurabh Kumar JhaDepartment of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida 201310, India.
King Abdulaziz University · SAChandigarh University · INGraphic Era University · INKR Mangalam University · INLovely Professional University · INParul University · INPresidency University · INSharda University · INUniversity of Sharjah · AEVisvesvaraya Technological University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlobally, diabetes mellitus is the most common cause of premature mortality after cardiovascular diseases and tobacco chewing. It is a heterogeneous metabolic disorder characterised by the faulty metabolism of carbohydrates, fats and proteins as a result of defects in insulin secretion or resistance. It was estimated that approximately 463 million of the adult population are suffering from diabetes mellitus, which may grow up to 700 million by 2045. PURPOSE: The present study aimed to evaluate the antioxidant, antidiabetic and anti-hyperlipidaemic activity of methanolic fruit extract of

methodExperimentally, type II diabetes was induced in rats by an i.p. injection of STZ at a dose of 60 mg/kg. The effect of the fruit extract was evaluated at doses of 100 and 200 mg/kg body weight in STZ-induced diabetic rats for 30 days.

resultThe oral administration of fruit extract caused a significant (

conclusionThe result confirmed that the fruit extract of

Indexed as

antidiabeticantioxidantslipid profileSolanum indicumstreptozotocin

Identifiers

PMID36826003
PMCPMC9954837
OpenAlexW4317435123

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.