Evidence map›Paper›PMID 36826751›Full record

ArticleDrugs & aging2023

New Migraine Drugs for Older Adults.

Dilara Onan, William David Wells-Gatnik, Enrico Bentivegna, Christian Lampl, Paolo Martelletti

Abstract read
PubMed Publisher
In one paragraph

Article in Drugs & aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Dilara OnanDepartment of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.ORCID http://orcid.org/0000-0001-9505-6135
William David Wells-GatnikDepartment of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.
Enrico BentivegnaDepartment of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.ORCID http://orcid.org/0000-0001-6655-9905
Christian LamplDepartment of Neurology and Headache Medical Centre, Konventhospital Barmherzige Brüder Linz, Seilerstätte 2, 4021, Linz, Austria.ORCID http://orcid.org/0000-0003-1756-1181
Paolo MartellettiDepartment of Clinical and Molecular Medicine, Sapienza University, Rome, Italy. paolo.martelletti@uniroma1.it.ORCID http://orcid.org/0000-0002-6556-4128
Sapienza University of Rome · ITConvent Hospital of the Brothers of Saint John of God · ATHacettepe University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraine is one of the most widespread and burdensome diseases, affecting one in every seven individuals in the world, for an estimated global prevalence of 14%. Until recently, therapeutic choices for older migraineurs have been limited by safety concerns and such patients have typically been excluded from clinical trials. However, randomized controlled trials (RCTs) of new migraine drugs have begun to include participants aged over 65 years, offering clinicians relevant safety and efficacy data to be able to treat older patients with the newest drug classes, including monoclonal antibodies for CGRP (r), CGRP antagonists, and drugs targeting the serotonin 5-HT

Indexed as

Calcitonin Gene-Related PeptideMigraine DisordersAgedAntibodies, MonoclonalHumansAntibodies, MonoclonalCalcitonin Gene-Related Peptide

Identifiers

PMID36826751
OpenAlexW4321749349

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.