SynthesisJournal of medical Internet research2023
Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review.
Synthesis in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07004231 (Using Gout Buddy to Enhance Dietary Literacy and Gout Management-A Mixed Method Clinical Trial), which is not on this map. Cited by 280 papers, 14 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Using Gout Buddy to Enhance Dietary Literacy and Gout Management-A Mixed Method Clinical Trial
Who cites it
280 citing papers in PubMed, 14 syntheses or guidelines pooled it.
- Robot-Assisted Oral Examination: Challenges and Innovations.International dental journal · 2026Pooled it
- Artificial Intelligence in Self-Management of Gestational Diabetes Mellitus: A Systematic Review.Journal of medical systems · 2026Pooled it
- Efficacy, User Engagement, and Acceptability of Cognitive Behavioral Therapy-Oriented Psychological Chatbots for Adults With Depressive and/or Anxiety Symptoms: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Machine Learning for the Analysis of Healthy Lifestyle Data: Scoping Review and Guidelines.JMIR human factors · 2026Guideline
- Effectiveness of chatbot interventions in individuals for hypertension management: a systematic review and narrative synthesis.Frontiers in digital health · 2026Pooled it
- Conversational agent-based interventions for lifestyle behavior modification in older adults: a systematic review.Systematic reviews · 2025Pooled it
- Pooled it
- The Effectiveness and Feasibility of Conversational Agents in Supporting Care for Patients With Cancer: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- User and Provider Experiences With Health Education Chatbots: Qualitative Systematic Review.JMIR human factors · 2025Pooled it
- Does the Digital Therapeutic Alliance Exist? Integrative Review.JMIR mental health · 2025Pooled it
- Systematic review exploring human, AI, and hybrid health coaching in digital health interventions: trends, engagement, and lifestyle outcomes.Frontiers in digital health · 2025Pooled it
- Revolutionizing e-health: the transformative role of AI-powered hybrid chatbots in healthcare solutions.Frontiers in public health · 2025Pooled it
- The Impact and Role of Artificial Intelligence (AI) in Healthcare: Systematic Review.Current topics in medicinal chemistry · 2025Pooled it
- A systematic review of artificial intelligence-powered (AI-powered) chatbot intervention for managing chronic illness.Annals of medicine · 2024Pooled it
- Trial
- The Effect of a WhatsApp Chatbot-Based Training Program on Infection Control Knowledge and Practices Among Hemodialysis Nurses: A Cluster-Randomized Controlled Trial.Journal of nursing management · 2026Trial
- DELTA: Strengthening human biological resilience with an N=1 digital health and dynamic biomarker protocol.PloS one · 2026Trial
- Bridging Technology and Pretest Genetic Services: Quantitative Study of Chatbot Interaction Patterns, User Characteristics, and Genetic Testing Decisions.Journal of medical Internet research · 2025Trial
- Experiences With a Multicomponent Digital Behavioral Pain Management Intervention for Adults With Sickle Cell Disease: Qualitative Analysis of the CaRISMA Trial.JMIR human factors · 2025Trial
- A vaccine chatbot intervention for parents to improve HPV vaccination uptake among middle school girls: a cluster randomized trial.Nature medicine · 2025Trial
220 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundArtificial intelligence (AI)-based chatbots can offer personalized, engaging, and on-demand health promotion interventions.
objectiveThe aim of this systematic review was to evaluate the feasibility, efficacy, and intervention characteristics of AI chatbots for promoting health behavior change.
methodsA comprehensive search was conducted in 7 bibliographic databases (PubMed, IEEE Xplore, ACM Digital Library, PsycINFO, Web of Science, Embase, and JMIR publications) for empirical articles published from 1980 to 2022 that evaluated the feasibility or efficacy of AI chatbots for behavior change. The screening, extraction, and analysis of the identified articles were performed by following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines.
resultsOf the 15 included studies, several demonstrated the high efficacy of AI chatbots in promoting healthy lifestyles (n=6, 40%), smoking cessation (n=4, 27%), treatment or medication adherence (n=2, 13%), and reduction in substance misuse (n=1, 7%). However, there were mixed results regarding feasibility, acceptability, and usability. Selected behavior change theories and expert consultation were used to develop the behavior change strategies of AI chatbots, including goal setting, monitoring, real-time reinforcement or feedback, and on-demand support. Real-time user-chatbot interaction data, such as user preferences and behavioral performance, were collected on the chatbot platform to identify ways of providing personalized services. The AI chatbots demonstrated potential for scalability by deployment through accessible devices and platforms (eg, smartphones and Facebook Messenger). The participants also reported that AI chatbots offered a nonjudgmental space for communicating sensitive information. However, the reported results need to be interpreted with caution because of the moderate to high risk of internal validity, insufficient description of AI techniques, and limitation for generalizability.
conclusionsAI chatbots have demonstrated the efficacy of health behavior change interventions among large and diverse populations; however, future studies need to adopt robust randomized control trials to establish definitive conclusions.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.