Evidence map›Paper›PMID 36829699›Full record

ArticleBioengineering (Basel, Switzerland)2023

Electrocardiography Assessment of Sympatico-Vagal Balance during Resting and Pain Using the Texas Instruments ADS1299.

Donghua Liao, Rasmus B Nedergaard, Misbah Unnisa, Soumya J Mahapatra, Mahya Faghih, Anna E Phillips, Dhiraj Yadav, Vikesh K Singh, Søren S Olesen, Rupjyoti Talukdar and 5 more

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Donghua LiaoMech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, 9000 Aalborg, Denmark.
Rasmus B NedergaardMech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, 9000 Aalborg, Denmark.ORCID 0000-0003-3271-1408
Misbah UnnisaDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.
Soumya J MahapatraDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi 110016, India.
Mahya FaghihDivision of Gastroenterology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
Anna E PhillipsDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Dhiraj YadavDivision of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Vikesh K SinghDivision of Gastroenterology, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA.
Søren S OlesenMech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, 9000 Aalborg, Denmark.
Rupjyoti TalukdarDepartment of Medical Gastroenterology, Asian Institute of Gastroenterology, Hyderabad 500082, India.
Pramod K GargDepartment of Gastroenterology, All India Institute of Medical Sciences, New Delhi 110016, India.
Imran K NiaziCentre for Chiropractic Research, New Zealand College of Chiropractic, Auckland 1060, New Zealand.ORCID 0000-0001-8752-7224
Christina BrockMech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, 9000 Aalborg, Denmark.
Asbjørn M DrewesMech-Sense, Department of Gastroenterology and Hepatology, Aalborg University Hospital, 9000 Aalborg, Denmark.ORCID 0000-0001-7465-964X
P-QST Consortium

Funding

Aalborg University Hospital INPAIN
6 · The paper itself

Abstract

Sympatico-vagal balance is essential for regulating cardiac electrophysiology and plays an important role in arrhythmogenic conditions. Various noninvasive methods, including electrocardiography (ECG), have been used for clinical assessment of the sympatico-vagal balance. This study aimed to use a custom-designed wearable device to record ECG and ECG-based cardiac function biomarkers to assess sympatico-vagal balance during tonic pain in healthy controls. Nineteen healthy volunteers were included for the ECG measurements using the custom-designed amplifier based on the Texas Instruments ADS1299. The ECG-based biomarkers of the sympatico-vagal balance, (including heart rate variability, deceleration capacity of the heart rate, and periodic repolarization dynamic), were calculated and compared between resting and pain conditions (tonic pain). The custom-designed device provided technically satisfactory ECG recordings. During exposure to tonic pain, the periodic repolarization dynamics increased significantly (

Indexed as

biomarkerscold pressor testelectrocardiography (ECG)sympatico–vagal balance

Identifiers

PMID36829699
PMCPMC9952434

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.