Evidence map›Paper›PMID 36829793›Full record

ArticleAntioxidants (Basel, Switzerland)2023

An Interplay between Oxidative Stress (Lactate Dehydrogenase) and Inflammation (Anisocytosis) Mediates COVID-19 Severity Defined by Routine Clinical Markers.

Marta Alonso-Bernáldez, Amanda Cuevas-Sierra, Víctor Micó, Andrea Higuera-Gómez, Omar Ramos-Lopez, Lidia Daimiel, Alberto Dávalos, María Martínez-Urbistondo, Víctor Moreno-Torres, Ana Ramirez de Molina and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Marta Alonso-BernáldezPrecision Nutrition and Cardiometabolic Health, IMDEA Food Institute, CEI UAM+CSIC, 28049 Madrid, Spain.
Amanda Cuevas-SierraPrecision Nutrition and Cardiometabolic Health, IMDEA Food Institute, CEI UAM+CSIC, 28049 Madrid, Spain.
Víctor MicóPrecision Nutrition and Cardiometabolic Health, IMDEA Food Institute, CEI UAM+CSIC, 28049 Madrid, Spain.ORCID 0000-0003-0681-7962
Andrea Higuera-GómezPrecision Nutrition and Cardiometabolic Health, IMDEA Food Institute, CEI UAM+CSIC, 28049 Madrid, Spain.ORCID 0000-0002-8680-6704
Omar Ramos-LopezMedicine and Psychology School, Autonomous University of Baja California, Tijuana 22390, Mexico.ORCID 0000-0002-2505-1555
Lidia DaimielCentro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28049 Madrid, Spain.ORCID 0000-0001-9898-6629
Alberto DávalosCentro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28049 Madrid, Spain.
María Martínez-UrbistondoPuerta de Hierro Research Institute, University Hospital, Majadahonda, 28222 Madrid, Spain.
Víctor Moreno-TorresPuerta de Hierro Research Institute, University Hospital, Majadahonda, 28222 Madrid, Spain.ORCID 0000-0002-9798-4514
Ana Ramirez de MolinaMolecular Oncology and Nutritional Genomics of Cancer Group, IMDEA Food Institute, CEI UAM+CSIC, 28049 Madrid, Spain.ORCID 0000-0003-1439-7494
Juan Antonio VargasPuerta de Hierro Research Institute, University Hospital, Majadahonda, 28222 Madrid, Spain.
J Alfredo MartinezPrecision Nutrition and Cardiometabolic Health, IMDEA Food Institute, CEI UAM+CSIC, 28049 Madrid, Spain.
Madrid Institute for Advanced Studies · ESHospital Universitario Puerta de Hierro Majadahonda · ESUniversidad Autónoma de Baja California · MXUniversidad Francisco de Vitoria · ES

Funding

Comunidad de Madrid METAINFLAMATION-Y2020/BIO-6600.European Regions Research and Innovation Network COVID-19, FACINGLCOVID-CM
6 · The paper itself

Abstract

Viral infections activate the innate immune response and the secretion of inflammatory cytokines. They also alter oxidative stress markers, which potentially can have an involvement in the pathogenesis of the disease. The aim of this research was to study the role of the oxidative stress process assessed through lactate dehydrogenase (LDH) on the severity of COVID-19 measured by oxygen saturation (SaO

Indexed as

anisocytosisCOVID-19interactionLDHoxidative stress

Identifiers

PMID36829793
PMCPMC9951932
OpenAlexW4317622050

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.