Evidence map›Paper›PMID 36830876›Full record

ArticleBiomedicines2023

Impaired Function of Solute Carrier Family 19 Leads to Low Folate Levels and Lipid Droplet Accumulation in Hepatocytes.

Ainara Cano, Mercedes Vazquez-Chantada, Javier Conde-Vancells, Aintzane Gonzalez-Lahera, David Mosen-Ansorena, Francisco J Blanco, Karine Clément, Judith Aron-Wisnewsky, Albert Tran, Philippe Gual and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Ainara CanoFood Research, AZTI, Basque Research and Technology Alliance (BRTA), Parque Tecnologico de Bizkaia, Astondo Bidea, Building 609, 48160 Derio, Spain.ORCID 0000-0001-6019-8926
Mercedes Vazquez-ChantadaOWL Metabolomics, Parque Tecnologico de Bizkaia, Building 502, 48160 Derio, Spain.
Javier Conde-VancellsDepartment of Nutritional Sciences, Dell Paediatric Research Institute, The University of Texas at Austin, Austin, TX 78712, USA.
Aintzane Gonzalez-LaheraCIC bioGUNE, Parque Tecnologico de Bizkaia, Building 801-A, 48160 Derio, Spain.
David Mosen-AnsorenaCIC bioGUNE, Parque Tecnologico de Bizkaia, Building 801-A, 48160 Derio, Spain.
Francisco J BlancoCIC bioGUNE, Parque Tecnologico de Bizkaia, Building 801-A, 48160 Derio, Spain.ORCID 0000-0003-2545-4319
Karine ClémentNutriomics Research Group, Nutrition Department, Pitié-Salpétrière Hospital, INSERM, Sorbonne Université, F-75013 Paris, France.
Judith Aron-WisnewskyNutriomics Research Group, Nutrition Department, Pitié-Salpétrière Hospital, INSERM, Sorbonne Université, F-75013 Paris, France.ORCID 0000-0002-3104-9769
Albert TranTeam 8 "Chronic Liver Diseases Associated with Obesity and Alcohol", INSERM, U1065, Centre Hospitalier Universitaire de Nice, C3M, Université Côte d'Azur, 06000 Nice, France.
Philippe GualTeam 8 "Chronic Liver Diseases Associated with Obesity and Alcohol", INSERM, U1065, Centre Hospitalier Universitaire de Nice, C3M, Université Côte d'Azur, 06000 Nice, France.
Carmelo García-MonzónCIBERehd, ISCIII, 28029 Madrid, Spain.ORCID 0000-0002-2118-8706
Joan CaballeríaCIBERehd, ISCIII, 28029 Madrid, Spain.
Azucena CastroOWL Metabolomics, Parque Tecnologico de Bizkaia, Building 502, 48160 Derio, Spain.
María Luz Martínez-ChantarCIC bioGUNE, Parque Tecnologico de Bizkaia, Building 801-A, 48160 Derio, Spain.ORCID 0000-0002-6446-9911
José M MatoCIC bioGUNE, Parque Tecnologico de Bizkaia, Building 801-A, 48160 Derio, Spain.
Huiping ZhuDepartment of Nutritional Sciences, Dell Paediatric Research Institute, The University of Texas at Austin, Austin, TX 78712, USA.
Richard H FinnellDepartment of Nutritional Sciences, Dell Paediatric Research Institute, The University of Texas at Austin, Austin, TX 78712, USA.ORCID 0000-0002-5962-8754
Ana M AransayCIC bioGUNE, Parque Tecnologico de Bizkaia, Building 801-A, 48160 Derio, Spain.ORCID 0000-0002-8271-612X
Instituto de Salud Carlos III · ESInserm · FREuskadiko Parke Teknologikoa · ESThe University of Texas at Austin · USCIC bioGUNE · ESIkerbasque · ES

Funding

Basque Foundation for Health Innovation and Research and BBVA Foundation sabatical year to RHFBasque Government Departamento de Salud 2013111114EITB Maratoia BIO15/CA/014European Union Seventh Framework Program FP7/2007-2013, under grant agreement n° Health-F2-2009-241762FLIP and Horizon 2020 Framework Program EPoS, grant #634413French Government (National Research Agency, ANR, #ANR-15-CE14-0016-0)Innovation Technology Department of the Bizkaia County 2005-2022 programsINSERM (France) and Association Française pour l'Etude du Foie to AFEFInstituto de Salud Carlos III 13/01299 and 17/00535Instituto de Salud Carlos III PIE/00031 and CIBERehdLa Caixa Foundation ID425Ministry of Economy, Industry and Competitiveness SAF2014-54658-R; CTQ2014-56966-R and PID2020-113225GB-I00Ministry of Economy, Industry and Competitiveness Severo Ochoa Excellence Accreditation (SEV-2016-0644)National Institute of Health HD081216, HD083809 and ES021006Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo FIT010000-2005-0013Programme Hospitalier de Reserche Clinique» Assistance Publique-Hôpitaux de Paris AOR 02076The Commission of the European Communities (Collaborative Project "Hepatic and adipose tissue and functions in the metabolic syndrome" HEPADIP, contract LSHM-CT-2005-018734)The Department of Industry, Tourism and Trade of the Government of the Autonomous Community of the Basque Country Etortek, Emaitek and Elkartek Research Programs 2005-2021
6 · The paper itself

Abstract

Low serum folate levels are inversely related to metabolic associated fatty liver disease (MAFLD). The role of the folate transporter gene (

Indexed as

folate cyclegenomicsliver lipid metabolismMAFLDmetabolomicsNAFLDSNPstranscriptomics

Identifiers

PMID36830876
PMCPMC9953281
OpenAlexW4318055105

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.