Evidence map›Paper›PMID 36831760›Full record

ArticleBrain sciences2023

Evaluation of High Intracranial Plaque Prevalence in Type 2 Diabetes Using Vessel Wall Imaging on 7 T Magnetic Resonance Imaging.

Masaharu Shozushima, Futoshi Mori, Satoshi Yashiro, Yusuke Todate, Tomoyasu Oda, Kan Nagasawa, Yutaka Hasegawa, Noriko Takebe, Makoto Sasaki, Yasushi Ishigaki

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Masaharu ShozushimaDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Iwate Medical University, Yahaba 028-3695, Japan.
Futoshi MoriDivision of Ultra-high Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Yahaba 028-3694, Japan.ORCID 0000-0002-3698-2507
Satoshi YashiroDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Iwate Medical University, Yahaba 028-3695, Japan.
Yusuke TodateDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Iwate Medical University, Yahaba 028-3695, Japan.
Tomoyasu OdaDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Iwate Medical University, Yahaba 028-3695, Japan.
Kan NagasawaDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Iwate Medical University, Yahaba 028-3695, Japan.
Yutaka HasegawaDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Iwate Medical University, Yahaba 028-3695, Japan.
Noriko TakebeDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Iwate Medical University, Yahaba 028-3695, Japan.
Makoto SasakiDivision of Ultra-high Field MRI, Institute for Biomedical Sciences, Iwate Medical University, Yahaba 028-3694, Japan.ORCID 0000-0002-3108-4361
Yasushi IshigakiDivision of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine, Iwate Medical University, Yahaba 028-3695, Japan.ORCID 0000-0003-2479-5752
Iwate Medical University · JP

Funding

Grants-in-Aid for Scientific Research JP22K08676Japan Agency for Medical Research and Development JP20am0101086
6 · The paper itself

Abstract

backgroundWhile type 2 diabetes (T2D) is a major risk for ischemic stroke, the associated vessel wall characteristics remain essentially unknown. This study aimed to clarify intracranial vascular changes on three-dimensional vessel wall imaging (3D-VWI) using fast spin echo by employing 7Tesla (7T) magnetic resonance imaging (MRI) in T2D patients without advanced atherosclerosis as compared to healthy controls.

methodsIn 48 T2D patients and 35 healthy controls, the prevalence of cerebral small vessel diseases and intracranial plaques were evaluated by 3D-VWI with 7T MRI.

resultsThe prevalence rate of lacunar infarction was significantly higher in T2D than in controls (

conclusionThis is the first study to demonstrate the high prevalence of intracranial plaque in T2D patients with neither confirmed atherosclerotic disease nor symptoms by performing intracranial 3D-VWI employing 7TMRI. Investigation of intracranial VWI with 7T MRI is expected to provide novel insights allowing early intensive risk management for prevention of ischemic stroke in T2D patients.

Indexed as

diabeteshigh resolution magnetic resonance imagingintracranial plaquesvessel wall imaging

Identifiers

PMID36831760
PMCPMC9954742
OpenAlexW4318476826

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.