Evidence map›Paper›PMID 36832113›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Imaging Diagnosis of Hepatocellular Carcinoma: A State-of-the-Art Review.

Gianvito Candita, Sara Rossi, Karolina Cwiklinska, Salvatore Claudio Fanni, Dania Cioni, Riccardo Lencioni, Emanuele Neri

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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  13. Early screening for liver cancer must be performed.World journal of hepatology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gianvito CanditaDepartment of Translational Research, Academic Radiology, University of Pisa, 56124 Pisa, Italy.
Sara RossiDepartment of Translational Research, Academic Radiology, University of Pisa, 56124 Pisa, Italy.
Karolina CwiklinskaDepartment of Translational Research, Academic Radiology, University of Pisa, 56124 Pisa, Italy.
Salvatore Claudio FanniDepartment of Translational Research, Academic Radiology, University of Pisa, 56124 Pisa, Italy.
Dania CioniDepartment of Translational Research, Academic Radiology, University of Pisa, 56124 Pisa, Italy.ORCID 0000-0002-5120-886X
Riccardo LencioniDepartment of Translational Research, Academic Radiology, University of Pisa, 56124 Pisa, Italy.
Emanuele NeriDepartment of Translational Research, Academic Radiology, University of Pisa, 56124 Pisa, Italy.ORCID 0000-0001-7950-4559
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) remains not only a cause of a considerable part of oncologic mortality, but also a diagnostic and therapeutic challenge for healthcare systems worldwide. Early detection of the disease and consequential adequate therapy are imperative to increase patients' quality of life and survival. Imaging plays, therefore, a crucial role in the surveillance of patients at risk, the detection and diagnosis of HCC nodules, as well as in the follow-up post-treatment. The unique imaging characteristics of HCC lesions, deriving mainly from the assessment of their vascularity on contrast-enhanced computed tomography (CT), magnetic resonance (MR) or contrast-enhanced ultrasound (CEUS), allow for a more accurate, noninvasive diagnosis and staging. The role of imaging in the management of HCC has further expanded beyond the plain confirmation of a suspected diagnosis due to the introduction of ultrasound and hepatobiliary MRI contrast agents, which allow for the detection of hepatocarcinogenesis even at an early stage. Moreover, the recent technological advancements in artificial intelligence (AI) in radiology contribute an important tool for the diagnostic prediction, prognosis and evaluation of treatment response in the clinical course of the disease. This review presents current imaging modalities and their central role in the management of patients at risk and with HCC.

Indexed as

artificial intelligencecomputed tomographyhepatocellular carcinomamagnetic resonance imagingultrasound

Identifiers

PMID36832113
PMCPMC9955560
OpenAlexW4319597915

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.