Evidence mapPaperPMID 36832145Full record

ArticleDiagnostics (Basel, Switzerland)2023

Tumor Stroma Area and Other Prognostic Factors in Pancreatic Ductal Adenocarcinoma Patients Submitted to Surgery.

Maria João Amaral, Mariana Amaral, João Freitas, Rui Caetano Oliveira, Marco Serôdio, Maria Augusta Cipriano, José Guilherme Tralhão

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Epigenetic regulation of the tumor microenvironment: A leading force driving pancreatic cancer.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2024
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria João AmaralGeneral Surgey Department, Centro Hospitalar e Universitário de Coimbra, 3000-075 Coimbra, Portugal.ORCID 0000-0002-7494-3218
Mariana AmaralFaculty of Medicine, Universiy of Coimbra, 3000-548 Coimbra, Portugal.ORCID 0000-0003-4144-0507
João FreitasFaculty of Medicine, Universiy of Coimbra, 3000-548 Coimbra, Portugal.
Rui Caetano OliveiraPathology Department, Centro Hospitalar e Universitário de Coimbra, 3000-075 Coimbra, Portugal.ORCID 0000-0002-7202-8059
Marco SerôdioGeneral Surgey Department, Centro Hospitalar e Universitário de Coimbra, 3000-075 Coimbra, Portugal.
Maria Augusta CiprianoPathology Department, Centro Hospitalar e Universitário de Coimbra, 3000-075 Coimbra, Portugal.
José Guilherme TralhãoGeneral Surgey Department, Centro Hospitalar e Universitário de Coimbra, 3000-075 Coimbra, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) has a dense stroma, responsible for up to 80% of its volume. The amount of stroma can be associated with prognosis, although there are discrepancies regarding its concrete impact. The aim of this work was to study prognostic factors for PDAC patients submitted to surgery, including the prognostic impact of the tumor stroma area (TSA). A retrospective study with PDAC patients submitted for surgical resection was conducted. The TSA was calculated using QuPath-0.2.3 software. Arterial hypertension, diabetes mellitus, and surgical complications Clavien-Dindo>IIIa are independent risk factors for mortality in PDAC patients submitted to surgery. Regarding TSA, using >1.9 × 10

Indexed as

pancreatic cancerprognosisstromasurvivaltumor microenvironment

Identifiers

PMID36832145
PMCPMC9955223

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.