Evidence map›Paper›PMID 36832273›Full record

ReviewDiagnostics (Basel, Switzerland)2023

The Role of Heart Rate Variability (HRV) in Different Hypertensive Syndromes.

Louise Buonalumi Tacito Yugar, Juan Carlos Yugar-Toledo, Nelson Dinamarco, Luis Gustavo Sedenho-Prado, Beatriz Vaz Domingues Moreno, Tatiane de Azevedo Rubio, Andre Fattori, Bruno Rodrigues, Jose Fernando Vilela-Martin, Heitor Moreno

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
23.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 110 citations in OpenAlex.

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  3. Smelling Wellness: Associations Between Botanic Garden Scentscapes and Human Health Gains.International journal of environmental research and public health · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Louise Buonalumi Tacito YugarSchool of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, SP, Brazil.
Juan Carlos Yugar-ToledoPost-Graduate Course in Medical Science, Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.
Nelson DinamarcoInternal Medicine Department, State University of Santa Cruz (UESC), Ilhéus 45662-900, BA, Brazil.ORCID 0000-0001-6031-048X
Luis Gustavo Sedenho-PradoSchool of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, SP, Brazil.
Beatriz Vaz Domingues MorenoCardiovascular Pharmacology & Hypertension Laboratory, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, SP, Brazil.
Tatiane de Azevedo RubioCardiovascular Pharmacology & Hypertension Laboratory, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, SP, Brazil.
Andre FattoriGeriatrics Department, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, SP, Brazil.
Bruno RodriguesLaboratory of Cardiovascular Investigation and Exercise, School of Physical Education, State University of Campinas (UNICAMP), Campinas 13083-887, SP, Brazil.
Jose Fernando Vilela-MartinPost-Graduate Course in Medical Science, Faculty of Medicine of São José do Rio Preto (FAMERP), São José do Rio Preto 15090-000, SP, Brazil.ORCID 0000-0001-6960-2825
Heitor MorenoCardiovascular Pharmacology & Hypertension Laboratory, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas 13083-887, SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BRFaculdade de Medicina de São José do Rio Preto · BRUniversidade Estadual de Santa Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac innervation by the parasympathetic nervous system (PNS) and the sympathetic nervous system (SNS) modulates the heart rate (HR) (chronotropic activity) and the contraction of the cardiac muscle (inotropic activity). The peripheral vasculature is controlled only by the SNS, which is responsible for peripheral vascular resistance. This also mediates the baroreceptor reflex (BR), which in turn mediates blood pressure (BP). Hypertension (HTN) and the autonomic nervous system (ANS) are closely related, such that derangements can lead to vasomotor impairments and several comorbidities, including obesity, hypertension, resistant hypertension, and chronic kidney disease. Autonomic dysfunction is also associated with functional and structural changes in target organs (heart, brain, kidneys, and blood vessels), increasing cardiovascular risk. Heart rate variability (HRV) is a method of assessing cardiac autonomic modulation. This tool has been used for clinical evaluation and to address the effect of therapeutic interventions. The present review aims (a) to approach the heart rate (HR) as a CV risk factor in hypertensive patients; (b) to analyze the heart rate variability (HRV) as a "tool" to estimate the individual risk stratum for Pre-HTN (P-HTN), Controlled-HTN (C-HTN), Resistant and Refractory HTN (R-HTN and Rf-HTN, respectively), and hypertensive patients with chronic renal disease (HTN+CKD).

Indexed as

autonomic dysfunctionchronic kidney diseaseheart rate variabilityhypertensionparasympathetic nervous systemprehypertensionresistant hypertensionsympathetic nervous system

Identifiers

PMID36832273
PMCPMC9955360
OpenAlexW4321372310

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.