Evidence map›Paper›PMID 36834246›Full record

Trial reportInternational journal of environmental research and public health2023

Acute Responses to High-Intensity Back Squats with Bilateral Blood Flow Restriction.

Bjoern Hornikel, Keith S Saffold, Michael R Esco, Jacob A Mota, Michael V Fedewa, Stefanie A Wind, Tiffany L Adams, Lee J Winchester

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in International journal of environmental research and public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07228780 (Impact of Resistance Training With and Without Venous Occlusion on Strength and Function Post Hand Burn), which is not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07228780 nacompletednot on this mapstarted 2025, after this paper: background citation

Impact of Resistance Training With and Without Venous Occlusion on Strength and Function Post Hand Burn

TypeinterventionalSponsorCairo UniversityRan2025 to 2026Enrolled34ConditionsHand BurnArmsresistance exercise with venous occlusion, traditional resistance exercises
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Acute Responses of Low-Load Resistance Exercise with Blood Flow Restriction.Journal of functional morphology and kinesiology · 2024
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bjoern HornikelDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Keith S SaffoldDepartment of Kinesiology, The University of Alabama, Tuscaloosa, AL 35487, USA.
Michael R EscoDepartment of Kinesiology, The University of Alabama, Tuscaloosa, AL 35487, USA.
Jacob A MotaDepartment of Kinesiology, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0002-4797-0173
Michael V FedewaDepartment of Kinesiology, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0002-2055-863X
Stefanie A WindDepartment of Educational Studies in Psychology, Research Methodology, and Counseling, The University of Alabama, Tuscaloosa, AL 35487, USA.
Tiffany L AdamsDepartment of Kinesiology, The University of Alabama, Tuscaloosa, AL 35487, USA.
Lee J WinchesterDepartment of Kinesiology, The University of Alabama, Tuscaloosa, AL 35487, USA.ORCID 0000-0001-8443-8429
University of Alabama · USTexas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the acute effects of high-intensity resistance exercise with blood flow restriction (BFR) on performance and fatigue, metabolic stress, and markers of inflammation (interleukin-6 (IL-6)), muscle damage (myoglobin), angiogenesis (vascular endothelial growth factor (VEGF)). Thirteen resistance-trained participants (four female, 24.8 ± 4.7 years) performed four sets of barbell back-squats (75% 1RM) to failure under two conditions: blood flow restriction (BFR, bilateral 80% occlusion pressure) and control (CTRL). Completed repetitions and pre-post-exercise changes in maximal voluntary isometric contractions, countermovement jump, barbell mean propulsive velocity, and surface electromyography were recorded. Pre-post blood lactate (BLa) and venous blood samples for analysis of IL-6, myoglobin, and VEGF were collected. Ratings of perceived exertion (RPE) and pain were recorded for each set. Fewer repetitions were performed during BFR (25.5 ± 9.6 reps) compared to CTRL (43.4 ± 14.2 reps,

Indexed as

Resistance TrainingVascular Endothelial Growth Factor AFatigueFemaleHumansInterleukin-6MaleMuscle, SkeletalMyoglobinPainRegional Blood FlowInterleukin-6MyoglobinVascular Endothelial Growth Factor Ablood flow restrictionfatiguemetabolic stressocclusion trainingresistance exercise

Identifiers

PMID36834246
PMCPMC9959773
OpenAlexW4321249094

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.