Evidence map›Paper›PMID 36834747›Full record

ArticleInternational journal of molecular sciences2023

Chronic Voluntary Alcohol Consumption Alters Promoter Methylation and Expression of

Leonie Herburg, Mathias Rhein, Sabrina Kubinski, Ekaterini Kefalakes, Matar Levin Greenwald, Simona Gielman, Segev Barak, Helge Frieling, Claudia Grothe

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Leonie HerburgInstitute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-8211-1104
Mathias RheinDepartment of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-1685-9843
Sabrina KubinskiInstitute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-7965-903X
Ekaterini KefalakesInstitute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0001-5074-9480
Matar Levin GreenwaldSchool of Psychological Sciences, Tel Aviv University, Tel Aviv 69978, Israel.ORCID 0000-0001-8010-8270
Simona GielmanDepartment of Neurobiology, The George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Segev BarakSchool of Psychological Sciences, Tel Aviv University, Tel Aviv 69978, Israel.ORCID 0000-0002-3143-6777
Helge FrielingCenter for Systems Neuroscience (ZSN), 30559 Hannover, Germany.
Claudia GrotheInstitute of Neuroanatomy and Cell Biology, Hannover Medical School, 30625 Hannover, Germany.ORCID 0000-0002-4683-0769
Medizinische Hochschule Hannover · DETel Aviv University · IL

Funding

Deutsche Forschungsgemeinschaft [GR 857/29-1 to CG]Israel Science Foundation GR 508/20 to SB
6 · The paper itself

Abstract

Alcohol abuse accounts for 3.3 million deaths annually, rendering it a global health issue. Recently, fibroblast growth factor 2 (FGF-2) and its target, fibroblast growth factor receptor 1 (FGFR1), were discovered to positively regulate alcohol-drinking behaviors in mice. We tested whether alcohol intake and withdrawal alter DNA methylation of

Indexed as

Fibroblast Growth Factor 2Receptor, Fibroblast Growth Factor, Type 1Alcohol DrinkingAnimalsDNA MethylationEthanolMiceReceptors, Fibroblast Growth FactorRNA, MessengerEthanolFgfr1 protein, mouseFibroblast Growth Factor 2Receptor, Fibroblast Growth Factor, Type 1Receptors, Fibroblast Growth FactorRNA, Messengeraddictionalcoholepigenetic alterationFGF-2FGFR1mesolimbic system

Identifiers

PMID36834747
PMCPMC9963845
OpenAlexW4319600120

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.