Evidence mapPaperPMID 36834823Full record

ArticleInternational journal of molecular sciences2023

Increased Aquaporin-7 Expression Is Associated with Changes in Rat Brown Adipose Tissue Whitening in Obesity: Impact of Cold Exposure and Bariatric Surgery.

Gema Frühbeck, Leire Méndez-Giménez, Sara Becerril, Beatriz Ramírez, Ana Wenting Hernández-Pardos, Javier A Cienfuegos, Víctor Valentí, Rafael Moncada, Victoria Catalán, Javier Gómez-Ambrosi and 3 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Gema FrühbeckMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-8305-7154
Leire Méndez-GiménezMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Sara BecerrilMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-3441-1970
Beatriz RamírezMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Ana Wenting Hernández-PardosMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Javier A CienfuegosDepartment of Surgery, Clínica Universidad de Navarra, 31008 Pamplona, Spain.
Víctor ValentíCentro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Rafael MoncadaCentro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Victoria CatalánMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-7513-7509
Javier Gómez-AmbrosiMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0001-5601-1604
Inês V da SilvaResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-004 Lisbon, Portugal.ORCID 0000-0002-2916-4848
Graça SoveralResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-004 Lisbon, Portugal.ORCID 0000-0001-8487-110X
Amaia RodríguezMetabolic Research Laboratory, Clínica Universidad de Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-2180-461X
Instituto de Salud Carlos III · ESClinica Universidad de Navarra · ESUniversity of Lisbon · PT

Funding

Instituto de Salud Carlos III CIBEROBNInstituto de Salud Carlos III PI19/00785Instituto de Salud Carlos III PI19/00990
6 · The paper itself

Abstract

Glycerol is a key metabolite for lipid accumulation in insulin-sensitive tissues. We examined the role of aquaporin-7 (AQP7), the main glycerol channel in adipocytes, in the improvement of brown adipose tissue (BAT) whitening, a process whereby brown adipocytes differentiate into white-like unilocular cells, after cold exposure or bariatric surgery in male Wistar rats with diet-induced obesity (DIO) (

Indexed as

AquaporinsBariatric SurgeryAdipose Tissue, BrownAnimalsEndothelial CellsGlycerolMaleObesityRatsRats, WistarAqp7 protein, ratAquaporinsGlyceroladipocyte hypertrophyaquaglyceroporinlipogenesisperoxisome proliferator-activated receptor γsleeve gastrectomy

Identifiers

PMID36834823
PMCPMC9963055
OpenAlexW4319761607

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.